BioCyc:RXN-20305
Ox-Tetraketide-Naphthomycin-PKS + 5 D-METHYL-MALONYL-COA + 5 MALONYL-COA + 8 NADPH + 18 PROTON --> Tetradecaketide-Naphthomycin-PKS + 10 CO-A + 8 NADP + 10 CARBON-DIOXIDE + 6 WATER
[] + 5 methylmalonyl-CoA(5-)[C25H35N7O19P3S] + 5 Malonyl-CoA[C24H38N7O19P3S] + 8 NADPH(4-)[C21H26N7O17P3] + 18 H+[H] = [] + 10 coenzyme A(4-)[C21H32N7O16P3S] + 8 NADP(3-)[C21H25N7O17P3] + 10 CO2[CO2] + 6 H2O[H2O]
DB Links
- BioCyc: RXN-20305
- EC Number: 2.3.1.-
Alias
- [BioCyc:RXN-20327] Amino-Hydroxybenzoyl-Ansatrienin-PKS + 2 D-METHYL-MALONYL-COA + 6 MALONYL-COA + 9 NADPH + 17 PROTON --> Nonaketide-Ansatrienin-PKS + 8 CO-A + 9 NADP + 8 CARBON-DIOXIDE + 5 WATER
- [BioCyc:RXN-20287] Ox-Tetraketide-Chaxamycin-PKS + 5 D-METHYL-MALONYL-COA + 2 MALONYL-COA + 6 NADPH + 13 PROTON --> Undecaketide-Chaxamycin-PKS + 7 CO-A + 6 NADP + 7 CARBON-DIOXIDE + 3 WATER
- [BioCyc:RXN-20305] Ox-Tetraketide-Naphthomycin-PKS + 5 D-METHYL-MALONYL-COA + 5 MALONYL-COA + 8 NADPH + 18 PROTON --> Tetradecaketide-Naphthomycin-PKS + 10 CO-A + 8 NADP + 10 CARBON-DIOXIDE + 6 WATER
- [BioCyc:RXN-17272] Long-Chain-acyl-PpsAE + 3 MALONYL-COA + 2 D-METHYL-MALONYL-COA + 5 NADPH + 10 PROTON --> Carboxyphthiodiolenone-PpsAE + 5 NADP + 2 WATER + 5 CARBON-DIOXIDE + 5 CO-A
- [BioCyc:RXN-20272] Ox-Tetraketide-Streptovaricin-PKS + 6 D-METHYL-MALONYL-COA + MALONYL-COA + 6 NADPH + 13 PROTON --> Streptovaricin-Undecaketide-PKS + 7 CO-A + 6 NADP + 7 CARBON-DIOXIDE + 3 WATER
Metabolites
Substrates
| metabolite | compartment | Structure |
|---|---|---|
Formula: |
Cytoplasm | |
| methylmalonyl-CoA(5-) Formula: C25H35N7O19P3S |
Cytoplasm | |
| Malonyl-CoA Formula: C24H38N7O19P3S |
Cytoplasm | |
| NADPH(4-) Formula: C21H26N7O17P3 |
Cytoplasm | |
| H+ Formula: H |
Cytoplasm |
Products
| metabolite | compartment | Structure |
|---|---|---|
Formula: |
Cytoplasm | |
| coenzyme A(4-) Formula: C21H32N7O16P3S |
Cytoplasm | |
| NADP(3-) Formula: C21H25N7O17P3 |
Cytoplasm | |
| CO2 Formula: CO2 |
Cytoplasm | |
| H2O Formula: H2O |
Cytoplasm |