jhd1 - Schizosaccharomyces pombe 972h-
Putative JmjC domain-containing histone demethylation protein 1
> jhd1 - Schizosaccharomyces pombe 972h- [Putative JmjC domain-containing histone demethylation protein 1]
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Metadata
Organism Source: 284812 - Schizosaccharomyces pombe 972h-
EC Number: 1.14.11.27
Cluster:
Registry Model:
Reactions
| reaction id | name | note |
|---|---|---|
| KEGG:R09510 | protein-N6,N6-dimethyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase | the first step of two-step reaction (see R10056, R09510+R09511) |
| KEGG:R09511 | protein-N6-methyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase | the second step of two-step reaction (see R10056, R09510+R09511) |
| KEGG:R10056 | protein-N6,N6-dimethyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase | two-step reaction (see R09510+R09511) |
| Rhea:RHEA:42033 | N6,N6-dimethyl-L-lysyl36-[histone H3] + 2 2-oxoglutarate + 2 O2 => L-lysyl36-[histone H3] + 2 formaldehyde + 2 succinate + 2 CO2 | Multi-step reaction: RHEA:21788 and RHEA:10784 |
| Rhea:RHEA:42034 | L-lysyl36-[histone H3] + 2 formaldehyde + 2 succinate + 2 CO2 => N6,N6-dimethyl-L-lysyl36-[histone H3] + 2 2-oxoglutarate + 2 O2 | Multi-step reaction: RHEA:21788 and RHEA:10784 |
| Rhea:RHEA:42035 | N6,N6-dimethyl-L-lysyl36-[histone H3] + 2 2-oxoglutarate + 2 O2 <=> L-lysyl36-[histone H3] + 2 formaldehyde + 2 succinate + 2 CO2 | Multi-step reaction: RHEA:21788 and RHEA:10784 |
| BioCyc:RXN-13186 | Histone-H3-K36m2 + 2 2-KETOGLUTARATE + 2 OXYGEN-MOLECULE --> Histone-H3-K36 + 2 SUC + 2 FORMALDEHYDE + 2 CARBON-DIOXIDE |
Pathways
| pathway id | name |
|---|---|
| Reactome:R-SPO-2299718 | Condensation of Prophase Chromosomes |
| Reactome:R-SPO-3247509 | Chromatin modifying enzymes |
| Reactome:R-SPO-1640170 | Cell Cycle |
| Reactome:R-SPO-4839726 | Chromatin organization |
| Reactome:R-SPO-3214842 | HDMs demethylate histones |
| Reactome:R-SPO-68886 | M Phase |
| Reactome:R-SPO-69278 | Cell Cycle, Mitotic |
| Reactome:R-SPO-68875 | Mitotic Prophase |