ale1 - Schizosaccharomyces pombe 972h-

Lysophospholipid acyltransferase

Acyltransferase Endoplasmic reticulum Lipid biosynthesis Lipid metabolism Membrane Microsome Phospholipid biosynthesis Phospholipid metabolism Phosphoprotein Reference proteome Transferase Transmembrane Transmembrane helix

Endoplasmic reticulum membrane Microsome membrane
> ale1 - Schizosaccharomyces pombe 972h- [Lysophospholipid acyltransferase]
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统计信息
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疏水性残基 0
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Metadata

Organism Source: 284812 - Schizosaccharomyces pombe 972h-
EC Number: 2.3.1.23 / 2.3.1.51
Cluster:
Registry Model:

Reactions

reaction id name note
KEGG:R01318 acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase Acyl-CoA + 1-Acyl-sn-glycero-3-phosphocholine <=> CoA + Phosphatidylcholine
KEGG:R02241 acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase Phosphatidate + CoA <=> 1-Acyl-sn-glycerol 3-phosphate + Acyl-CoA
KEGG:R02760 2,3-dehydroacyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase 2,3-Dehydroacyl-CoA + 1-Acyl-sn-glycerol 3-phosphate <=> CoA + Phosphatidate
KEGG:R03438 acyl-CoA:1-alkyl-sn-glycero-3-phosphocholine O-acyltransferase Acyl-CoA + 1-Organyl-2-lyso-sn-glycero-3-phosphocholine <=> CoA + 1-Radyl-2-acyl-sn-glycero-3-phosphocholine
KEGG:R04480 acyl-CoA:1-acyl-sn-glycero-3-phosphoethanolamine O-acyltransferase Phosphatidylethanolamine + CoA <=> 1-Acyl-sn-glycero-3-phosphoethanolamine + Acyl-CoA
KEGG:R09381 acyl-ACP:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase Acyl-[acyl-carrier protein] + 1-Acyl-sn-glycerol 3-phosphate <=> Acyl-carrier protein + Phosphatidate
BioCyc:RXN-1623 ACYL-COA + ACYL-SN-GLYCEROL-3P --> L-PHOSPHATIDATE + CO-A
BioCyc:RXN-17014 Cis-vaccenoyl-ACPs + 1-PALMITOYLGLYCEROL-3-PHOSPHATE --> CPD-18352 + ACP
BioCyc:RXN0-6705 1-PALMITOYLGLYCEROL-3-PHOSPHATE + Palmitoyl-ACPs --> CPD0-1422 + ACP This is the second step in de novo phospholipid biosynthesisin which a second fatty acid is esterified at C2 of the glycerolmoiety.This reaction, using the specific compound instances leading to the dipalmitoyl lipid, was needed for FBA, because the instantiation of the generic reaction failed for this case (because of an ambiguous match).
BioCyc:RXN-17010 CPD-18346 + 1-PALMITOYLGLYCEROL-3-PHOSPHATE --> CPD-18352 + CO-A
BioCyc:RXN-17021 TETRADECANOYL-COA + CPD-18379 --> CPD0-1425 + CO-A
BioCyc:RXN-17013 Palmitoleoyl-ACPs + CPD-18348 --> CPD-18351 + ACP
BioCyc:1-ACYLGLYCEROL-3-P-ACYLTRANSFER-RXN ACYL-SN-GLYCEROL-3P + ACYL-ACP --> L-PHOSPHATIDATE + ACP This is the second step in de novo phospholipid biosynthesisin which a second fatty acid is esterified at C2 of the glycerolmoiety.
BioCyc:RXN-17015 Cis-vaccenoyl-ACPs + CPD-18348 --> CPD-18353 + ACP
BioCyc:RXN-17019 CPD-10269 + CPD-18379 --> CPD-18380 + CO-A
BioCyc:RXN-17023 1-PALMITOYLGLYCEROL-3-PHOSPHATE + TETRADECANOYL-COA --> CPD-18390 + CO-A
BioCyc:RXN-17009 CPD-10269 + CPD-18348 --> CPD-18351 + CO-A
BioCyc:RXN-17022 Myristoyl-ACPs + CPD-18379 --> CPD0-1425 + ACP
BioCyc:RXN-17024 1-PALMITOYLGLYCEROL-3-PHOSPHATE + Myristoyl-ACPs --> CPD-18390 + ACP
BioCyc:RXN-17008 CPD-10269 + 1-PALMITOYLGLYCEROL-3-PHOSPHATE --> CPD-18350 + CO-A
BioCyc:RXN-17012 Palmitoleoyl-ACPs + 1-PALMITOYLGLYCEROL-3-PHOSPHATE --> CPD-18350 + ACP
BioCyc:RXN0-5514 1-acylglycerol-3-phosphate O-acyltransferase This is the second step in de novo phospholipid biosynthesisin which a second fatty acid is esterified at C2 of the glycerolmoiety.
BioCyc:RXN-17011 CPD-18346 + CPD-18348 --> CPD-18353 + CO-A
BioCyc:RXN-17020 Palmitoleoyl-ACPs + CPD-18379 --> CPD-18380 + ACP
Rhea:RHEA:12938 a 1-acyl-sn-glycero-3-phosphocholine + an acyl-CoA => a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
Rhea:RHEA:12939 a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA => a 1-acyl-sn-glycero-3-phosphocholine + an acyl-CoA
Rhea:RHEA:12940 a 1-acyl-sn-glycero-3-phosphocholine + an acyl-CoA <=> a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
Rhea:RHEA:19710 a 1-acyl-sn-glycero-3-phosphate + an acyl-CoA => a 1,2-diacyl-sn-glycero-3-phosphate + CoA
Rhea:RHEA:19711 a 1,2-diacyl-sn-glycero-3-phosphate + CoA => a 1-acyl-sn-glycero-3-phosphate + an acyl-CoA
Rhea:RHEA:19712 a 1-acyl-sn-glycero-3-phosphate + an acyl-CoA <=> a 1,2-diacyl-sn-glycero-3-phosphate + CoA
BioCyc:RXN-17688 CPD-17282 + CO-A<=>CPD-14018 + Glycerolipids
BioCyc:RXN-16032 PALMITYL-COA + ACYL-SN-GLYCEROL-3P --> 2-Palmitoyl-L-Phosphatidate + CO-A
BioCyc:RXN-16152 CPD-15366 + Glycerolipids --> CPD-17400 + CO-A
BioCyc:RXN-16045 Linoleoyl-groups + CO-A --> CPD-18 + Glycerolipids
BioCyc:RXN-16076 Stearoyl-ACPs + CPD0-2113 --> CPD0-1423 + ACP
BioCyc:RXN-16042 CPD-14394 + Glycerolipids --> CPD-17281 + CO-A
BioCyc:RXN-17729 ACYL-COA + 1-Alkyl-sn-glycerol-3-phosphates --> 1-Alkyl-2-acyl-glycerol-3-phosphate + CO-A
BioCyc:RXN-16067 ACYL-ACP + CPD0-2113 --> 1-Stearoyl-L-Phosphatidate + ACP
BioCyc:RXN-16150 CPD-15365 + Glycerolipids<=>CPD-17397 + CO-A
BioCyc:RXN-20565 ACYL-COA + 1-PALMITOYLGLYCEROL-3-PHOSPHATE --> 1-Palmitoyl-2-Acyl-Glycerol-P + CO-A
BioCyc:2.3.1.23-RXN ACYL-COA + 2-Lysophosphatidylcholines<=>PHOSPHATIDYLCHOLINE + CO-A
BioCyc:RXN-15043 OLEOYL-COA + L-1-LYSOPHOSPHATIDATE --> CPD-8268 + CO-A
BioCyc:RXN-16077 Oleoyl-ACPs + CPD0-2113 --> CPD-17319 + ACP
BioCyc:RXN-16043 Gamma-linolenoyl-groups + CO-A --> GAMMA-LINOLENOYL-COA + Glycerolipids
BioCyc:RXN-19425 CPD-15364 + 1-Acyl-sn-glycero-3-phosphocholines<=>CPD-18171 + CO-A
BioCyc:RXN-16157 CPD-15367 + Glycerolipids<=>CPD-17399 + CO-A
BioCyc:RXN-15036 OLEOYL-COA + CPD-8355<=>CPD-8291 + CO-A
BioCyc:RXN-9670 OLEOYL-COA + Glycerolipids<=>Oleoyl-lipid + CO-A
BioCyc:RXN-16151 CPD-15364 + Glycerolipids<=>CPD-17396 + CO-A
BioCyc:RXN-15066 PALMITYL-COA + CPD-8343<=>1-2-DIPALMITOYLPHOSPHATIDYLCHOLINE + CO-A
BioCyc:RXN-16118 CPD-17371 + CPD-17372 --> CPD-17373 + CO-A
BioCyc:RXN-16025 Palmitoyl-ACPs + CPD0-2113 --> CPD-17273 + ACP
BioCyc:RXN-16044 CPD-14407 + Glycerolipids --> CPD-17283 + CO-A
BioCyc:RXN-20528 ARACHIDONYL-COA + ACYL-SN-GLYCEROL-3P --> 1-Acyl-2-Arachidonoyl-Glycerol-P + CO-A
BioCyc:RXN-20512 ACYL-COA + CPD-22222 --> 1-Arachidonoyl-2-Acyl-Glycerol-P + CO-A
BioCyc:RXN-16041 CPD-17278 + CO-A --> CPD-14392 + Glycerolipids
BioCyc:RXN-16158 CPD-15363 + Glycerolipids<=>CPD-17404 + CO-A

Pathways

pathway id name
Reactome:R-SPO-1482922 Acyl chain remodelling of PI
Reactome:R-SPO-1430728 Metabolism
Reactome:R-SPO-1483206 Glycerophospholipid biosynthesis
Reactome:R-SPO-1482839 Acyl chain remodelling of PE
Reactome:R-SPO-1483257 Phospholipid metabolism
Reactome:R-SPO-1482801 Acyl chain remodelling of PS
Reactome:R-SPO-556833 Metabolism of lipids
Reactome:R-SPO-1482788 Acyl chain remodelling of PC