Pathways Knowlegdes
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| Pathway | DOIs | Note |
|---|---|---|
| ajmaline and sarpagine biosynthesis Accession ID: PlantCyc:PLANT_PWY-5301 |
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Ruppert M, Woll J, Giritch A, Genady E, Ma X, Stöckigt J. Functional expression of an ajmaline pathway-specific esterase from Rauvolfia in a novel plant-virus expression system. Planta. 2005 Nov;222(5):888–98. doi: 10.1007/s00425-005-0031-0. PMID: 16133216.; Bayer A, Ma X, Stöckigt J. Acetyltransfer in natural product biosynthesis--functional cloning and molecular analysis of vinorine synthase. Bioorg Med Chem. 2004 May 15;12(10):2787–95. doi: 10.1016/j.bmc.2004.02.029. PMID: 15110860.; Gao S, von Schumann G, Stöckigt J. A newly-detected reductase from Rauvolfia closes a gap in the biosynthesis of the antiarrhythmic alkaloid ajmaline. Planta Med. 2002 Oct;68(10):906–11. doi: 10.1055/s-2002-34935. PMID: 12391554.; Yu B, Ruppert M, Stöckigt J. Deoxysarpagine Hydroxylase — A Novel Enzyme Closing a Short Side Pathway of Alkaloid Biosynthesis in Rauvolfia. Bioorganic & Medicinal Chemistry. 2002 Aug;10(8):2479–83. doi: 10.1016/s0968-0896(02)00126-8.; von Schumann G, Gao S, Stöckigt J. Vomilenine reductase--a novel enzyme catalyzing a crucial step in the biosynthesis of the therapeutically applied antiarrhythmic alkaloid ajmaline. Bioorg Med Chem. 2002 Jun;10(6):1913–8. doi: 10.1016/s0968-0896(01)00435-7. PMID: 11937349.; Gerasimenko I, Sheludko Y, Ma X, Stöckigt J. Heterologous expression of a Rauvolfia cDNA encoding strictosidine glucosidase, a biosynthetic key to over 2000 monoterpenoid indole alkaloids. European Journal of Biochemistry. 2002 Apr;269(8):2204–13. doi: 10.1046/j.1432-1033.2002.02878.x. |
| ajmaline and sarpagine biosynthesis Accession ID: PlantCyc:CGIGANTEA_PWY-5301 |
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| ajmaline and sarpagine biosynthesis Accession ID: PlantCyc:CROSEUS_PWY-5301 |
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