Pathways Knowlegdes

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Pathway DOIs Note
styrene degradation

Accession ID: BioCyc:META_PWY-6941
  • 10.1128/aem.56.5.1347-1351.1990
  • 10.1128/aem.63.6.2232-2239.1997
 Beltrametti F, Marconi AM, Bestetti G, Colombo C, Galli E, Ruzzi M, Zennaro E. Sequencing and functional analysis of styrene catabolism genes from Pseudomonas fluorescens ST. Appl Environ Microbiol. 1997 Jun;63(6):2232–9. doi: 10.1128/aem.63.6.2232-2239.1997.; Hartmans S, van der Werf MJ, de Bont JA. Bacterial degradation of styrene involving a novel flavin adenine dinucleotide-dependent styrene monooxygenase. Appl Environ Microbiol. 1990 May;56(5):1347–51. doi: 10.1128/aem.56.5.1347-1351.1990.
superpathway of phenylethylamine degradation

Accession ID: BioCyc:META_PWY-6071
  • 10.1073/pnas.1005399107
  • 10.1099/00221287-133-2-347
  • 10.1099/00221287-143-2-513
 Teufel R, Mascaraque V, Ismail W, Voss M, Perera J, Eisenreich W, Haehnel W, Fuchs G. Bacterial phenylalanine and phenylacetate catabolic pathway revealed. Proc Natl Acad Sci U S A. 2010 Aug 10;107(32):14390–5. PMID: 20660314; PMCID: PMC2922514.; Hanlon SP, Hill TK, Flavell MA, Stringfellow JM, Cooper RA. 2-phenylethylamine catabolism by Escherichia coli K-12: gene organization and expression. Microbiology (Reading). 1997 Feb;143 ( Pt 2)():513–8. doi: 10.1099/00221287-143-2-513. PMID: 9043126.; Parrott S, Jones S, Cooper RA. 2-Phenylethylamine catabolism by Escherichia coli K12. J Gen Microbiol. 1987 Feb;133(2):347–51. doi: 10.1099/00221287-133-2-347. PMID: 3309152.
phenylethanol biosynthesis

Accession ID: BioCyc:META_PWY-5751
  • 10.1016/j.phytochem.2007.06.005
  • 10.1073/pnas.0602469103
  • 10.1074/jbc.275.19.14659
  • 10.1074/jbc.m211914200
  • 10.1074/jbc.m602708200
  • 10.1271/bbb.70090
 Tieman DM, Loucas HM, Kim JY, Clark DG, Klee HJ. Tomato phenylacetaldehyde reductases catalyze the last step in the synthesis of the aroma volatile 2-phenylethanol. Phytochemistry. 2007 Nov;68(21):2660–9. doi: 10.1016/j.phytochem.2007.06.005. PMID: 17644147.; SAKAI M, HIRATA H, SAYAMA H, SEKIGUCHI K, ITANO H, ASAI T, DOHRA H, HARA M, WATANABE N. Production of 2-Phenylethanol in Roses as the Dominant Floral Scent Compound fromL-Phenylalanine by Two Key Enzymes, a PLP-Dependent Decarboxylase and a Phenylacetaldehyde Reductase. Bioscience, Biotechnology, and Biochemistry. 2007 Oct 23;71(10):2408–19. doi: 10.1271/bbb.70090.; Kaminaga Y, Schnepp J, Peel G, Kish CM, Ben-Nissan G, Weiss D, Orlova I, Lavie O, Rhodes D, Wood K, Porterfield DM, Cooper AJL, Schloss JV, Pichersky E, Vainstein A, Dudareva N. Plant Phenylacetaldehyde Synthase Is a Bifunctional Homotetrameric Enzyme That Catalyzes Phenylalanine Decarboxylation and Oxidation. Journal of Biological Chemistry. 2006 Aug;281(33):23357–66. doi: 10.1074/jbc.m602708200.; Tieman D, Taylor M, Schauer N, Fernie AR, Hanson AD, Klee HJ. Tomato aromatic amino acid decarboxylases participate in synthesis of the flavor volatiles 2-phenylethanol and 2-phenylacetaldehyde. Proc Natl Acad Sci U S A. 2006 May 23;103(21):8287–92. PMID: 16698923; PMCID: PMC1472464.; Dickinson JR, Salgado LEJ, Hewlins MJE. The Catabolism of Amino Acids to Long Chain and Complex Alcohols in Saccharomyces cerevisiae. Journal of Biological Chemistry. 2003 Mar;278(10):8028–34. doi: 10.1074/jbc.m211914200.; Wittstock U, Halkier BA. Cytochrome P450 CYP79A2 from Arabidopsis thaliana L. Catalyzes the Conversion of l-Phenylalanine to Phenylacetaldoxime in the Biosynthesis of Benzylglucosinolate. Journal of Biological Chemistry. 2000 May;275(19):14659–66. doi: 10.1074/jbc.275.19.14659.
phenylethylamine degradation I

Accession ID: BioCyc:ECO_2PHENDEG-PWY
  • 10.1099/00221287-133-2-347
 Parrott S, Jones S, Cooper RA. 2-Phenylethylamine catabolism by Escherichia coli K12. J Gen Microbiol. 1987 Feb;133(2):347–51. doi: 10.1099/00221287-133-2-347. PMID: 3309152.
L-phenylalanine degradation II (anaerobic)

Accession ID: BioCyc:AGRO_ANAPHENOXI-PWY		 -
phenylethylamine degradation I

Accession ID: BioCyc:ECOL413997_2PHENDEG-PWY		 -
phenylalanine degradation IV (mammalian, via side chain)

Accession ID: BioCyc:THAPS_PWY-6318		 -
phenylethylamine degradation I

Accession ID: BioCyc:META_2PHENDEG-PWY
  • 10.1099/00221287-133-2-347
 Parrott S, Jones S, Cooper RA. 2-Phenylethylamine catabolism by Escherichia coli K12. J Gen Microbiol. 1987 Feb;133(2):347–51. doi: 10.1099/00221287-133-2-347. PMID: 3309152.
phenylethylamine degradation II

Accession ID: BioCyc:META_PWY-6534
  • 10.1111/j.1462-2920.2007.01464.x
 Arias S, Olivera ER, Arcos M, Naharro G, Luengo JM. Genetic analyses and molecular characterization of the pathways involved in the conversion of 2-phenylethylamine and 2-phenylethanol into phenylacetic acid in Pseudomonas putida U. Environmental Microbiology. 2007 Dec 27;10(2):413–32. doi: 10.1111/j.1462-2920.2007.01464.x.
L-phenylalanine degradation III

Accession ID: BioCyc:META_PWY-5079
  • 10.1074/jbc.m211914200
  • 10.1128/aem.69.8.4534-4541.2003
 Vuralhan Z, Morais MA, Tai S, Piper MDW, Pronk JT. Identification and Characterization of Phenylpyruvate Decarboxylase Genes in Saccharomyces cerevisiae. Appl Environ Microbiol. 2003 Aug;69(8):4534–41. doi: 10.1128/aem.69.8.4534-4541.2003.; Dickinson JR, Salgado LEJ, Hewlins MJE. The Catabolism of Amino Acids to Long Chain and Complex Alcohols in Saccharomyces cerevisiae. Journal of Biological Chemistry. 2003 Mar;278(10):8028–34. doi: 10.1074/jbc.m211914200.
glycine betaine biosynthesis I (Gram-negative bacteria)

Accession ID: BioCyc:ECO_BETSYN-PWY
  • 10.1128/jb.165.3.856-863.1986
 Styrvold OB, Falkenberg P, Landfald B, Eshoo MW, Bjørnsen T, Strøm AR. Selection, mapping, and characterization of osmoregulatory mutants of Escherichia coli blocked in the choline-glycine betaine pathway. J Bacteriol. 1986 Mar;165(3):856–63. doi: 10.1128/jb.165.3.856-863.1986.
phenylalanine degradation II (anaerobic)

Accession ID: BioCyc:TRYPANO_ANAPHENOXI-PWY		 -
phenylalanine degradation III

Accession ID: BioCyc:PLASMO_PWY-5079		 -
L-phenylalanine degradation II (anaerobic)

Accession ID: BioCyc:SCO_ANAPHENOXI-PWY		 -
phenylethylamine degradation I

Accession ID: BioCyc:SCO_2PHENDEG-PWY		 -
phenylalanine degradation III

Accession ID: BioCyc:PCHR_PWY-5079		 -
superpathway of phenylethylamine degradation

Accession ID: BioCyc:ECO_PWY-6071		 -
phenylalanine degradation

Accession ID: BioCyc:YEAST_PWY-5079		 -
phenylethanol biosynthesis

Accession ID: BioCyc:SMAN_PWY-5751		 -
phenylethylamine degradation I

Accession ID: BioCyc:ECOL316407_2PHENDEG-PWY		 -