Pathways Knowlegdes

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Pathway DOIs Note
folate metabolism

Accession ID: BioCyc:LEISH_PWY3IU-235
  • 10.1016/j.pt.2007.02.004
  • 10.1016/s0020-7519(01)00346-0
  • 10.1111/j.1365-2958.2009.06610.x
 Murta SMF, Vickers TJ, Scott DA, Beverley SM. Methylene tetrahydrofolate dehydrogenase/cyclohydrolase and the synthesis of 10-CHO-THF are essential inLeishmania major. Molecular Microbiology. 2009 Mar;71(6):1386–401. doi: 10.1111/j.1365-2958.2009.06610.x.; Opperdoes FR, Coombs GH. Metabolism of Leishmania: proven and predicted. Trends Parasitol. 2007 Apr;23(4):149–58. doi: 10.1016/j.pt.2007.02.004. PMID: 17320480.; Ouellette M, Drummelsmith J, El Fadili A, Kündig C, Richard D, Roy G. Pterin transport and metabolism in Leishmania and related trypanosomatid parasites. International Journal for Parasitology. 2002 Apr;32(4):385–98. doi: 10.1016/s0020-7519(01)00346-0.
pyrimidine deoxyribonucleotides de novo biosynthesis I

Accession ID: BioCyc:LEISH_PWY0-166		 -
purine and pyrimidine metabolism

Accession ID: BioCyc:TRYPANO_P1-PWY		 -
pyrimidine deoxyribonucleotides de novo biosynthesis I

Accession ID: BioCyc:TRYPANO_PWY0-166		 -
formylTHF biosynthesis II

Accession ID: BioCyc:TRYPANO_PWY-3841		 -
salvage pathways of pyrimidine deoxyribonucleotides

Accession ID: BioCyc:CALBI_YEAST-SALV-PYRMID-DNTP
  • 10.1007/s00294-002-0296-9
  • 10.1007/s002940050482
 Kurtz JE, Exinger F, Erbs P, Jund R. The URH1 uridine ribohydrolase of Saccharomyces cerevisiae. Curr Genet. 2002 Jun;41(3):132–41. doi: 10.1007/s00294-002-0296-9. PMID: 12111094.; Kurtz JE, Exinger F, Erbs P, Jund R. New insights into the pyrimidine salvage pathway of Saccharomyces cerevisiae: requirement of six genes for cytidine metabolism. Curr Genet. 1999 Sep;36(3):130–6. doi: 10.1007/s002940050482. PMID: 10501935.
pyrimidine deoxyribonucleotides de novo biosynthesis

Accession ID: BioCyc:CALBI_PWY0-166
  • 10.1007/bf00309928
  • 10.1128/jb.171.3.1372-1378.1989
 McIntosh EM, Looser J, Haynes RH, Pearlman RE. MluI site-dependent transcriptional regulation of the Candida albicans dUTPase gene. Curr Genet. 1994 Nov;26(5-6):415–21. doi: 10.1007/bf00309928. PMID: 7874734.; Singer SC, Richards CA, Ferone R, Benedict D, Ray P. Cloning, purification, and properties of Candida albicans thymidylate synthase. J Bacteriol. 1989 Mar;171(3):1372–8. doi: 10.1128/jb.171.3.1372-1378.1989.
salvage pathways of pyrimidine deoxyribonucleotides

Accession ID: BioCyc:LEISH_PWY0-181		 -
salvage pathways of pyrimidine deoxyribonucleotides

Accession ID: BioCyc:TRYPANO_PWY0-181		 -
formylTHF biosynthesis I

Accession ID: BioCyc:TRYPANO_1CMET2-PWY		 -
folate transformations II

Accession ID: BioCyc:CALBI_PWY-3841
  • 10.1093/jac/dkl124
 Navarro-Martínez MD, García-Cánovas F, Rodríguez-López JN. Tea polyphenol epigallocatechin-3-gallate inhibits ergosterol synthesis by disturbing folic acid metabolism in Candida albicans. J Antimicrob Chemother. 2006 Jun;57(6):1083–92. doi: 10.1093/jac/dkl124. PMID: 16585130.
Pyrimidine Metabolism

Accession ID: PathBank:SMP0000959		 -
One Carbon Pool by Folate

Accession ID: PathBank:SMP0001750		 -
Salvage Pathways of Pyrimidine Deoxyribonucleotides

Accession ID: PathBank:SMP0002073		 -
Trans-sulfuration, one-carbon metabolism and related pathways

Accession ID: WikiPathways:WP2525
  • 10.1016/j.cmet.2016.08.009
 Ducker GS, Rabinowitz JD. One-Carbon Metabolism in Health and Disease. Cell Metabolism. 2017 Jan;25(1):27–42. doi: 10.1016/j.cmet.2016.08.009.
Biochemical pathways: part I

Accession ID: WikiPathways:WP3604
  • 10.1016/s0303-2647(98)00019-7
 Michal G. On representation of metabolic pathways. Biosystems. 1998 Jun;47(1-2):1–7. doi: 10.1016/s0303-2647(98)00019-7. PMID: 9715748.
One-carbon metabolism

Accession ID: WikiPathways:WP435
  • 10.1093/carcin/bgm062
 Hazra A, Wu K, Kraft P, Fuchs CS, Giovannucci EL, Hunter DJ. Twenty-four non-synonymous polymorphisms in the one-carbon metabolic pathway and risk of colorectal adenoma in the Nurses' Health Study. Carcinogenesis. 2007 Jul;28(7):1510–9. doi: 10.1093/carcin/bgm062. PMID: 17389618.
One-carbon metabolism

Accession ID: WikiPathways:WP1026
  • 10.1146/annurev.biochem.66.1.269
 Ludwig ML, Matthews RG. STRUCTURE-BASED PERSPECTIVES ON B12-DEPENDENT ENZYMES. Annu. Rev. Biochem. 1997 Jun;66(1):269–313. doi: 10.1146/annurev.biochem.66.1.269.
Fluoropyrimidine activity

Accession ID: WikiPathways:WP3275
  • 10.1211/0022357055966
 Kobayashi Y, Ohshiro N, Sakai R, Ohbayashi M, Kohyama N, Yamamoto T. Transport mechanism and substrate specificity of human organic anion transporter 2 (hOat2 [SLC22A7]). J Pharm Pharmacol. 2005 May;57(5):573–8. doi: 10.1211/0022357055966. PMID: 15901346.
Ethanol effects on histone modifications

Accession ID: WikiPathways:WP3996
  • 10.1038/nrm2145
 Lee KK, Workman JL. Histone acetyltransferase complexes: one size doesn't fit all. Nature Reviews Molecular Cell Biology. 2007 Apr;8(4):284–95. doi: 10.1038/nrm2145.