Pathways Knowlegdes

Necessitatibus eius consequatur ex aliquid fuga eum quidem sint consectetur velit

Pathway DOIs Note
noradrenaline and adrenaline degradation

Accession ID: BioCyc:THAPS_PWY-6342		 -
Neurotransmitter release cycle

Accession ID: Reactome:R-BTA-112310
  • 10.1007/s00441-006-0243-z
  • 10.1007/s00441-006-0244-y
  • 10.1016/j.neuron.2007.09.001
  • 10.1146/annurev.neuro.26.041002.131412
 Edwards RH. The neurotransmitter cycle and quantal size. Neuron. 2007 Sep 20;55(6):835–58. doi: 10.1016/j.neuron.2007.09.001. PMID: 17880890.; Schoch S, Gundelfinger ED. Molecular organization of the presynaptic active zone. Cell Tissue Res. 2006 Nov;326(2):379–91. doi: 10.1007/s00441-006-0244-y. PMID: 16865347.; Becherer U, Rettig J. Vesicle pools, docking, priming, and release. Cell Tissue Res. 2006 Nov;326(2):393–407. doi: 10.1007/s00441-006-0243-z. PMID: 16819626.; Sudhof TC. The synaptic vesicle cycle. Annu Rev Neurosci. 2004;27():509–47. doi: 10.1146/annurev.neuro.26.041002.131412. PMID: 15217342.
Transmission across Chemical Synapses

Accession ID: Reactome:R-CFA-112315		 -
Transmission across Chemical Synapses

Accession ID: Reactome:R-DRE-112315		 -
Norepinephrine Neurotransmitter Release Cycle

Accession ID: Reactome:R-DDI-181430
  • 10.1038/nsmb1305
  • 10.1074/jbc.m211114200
  • 10.1126/science.1142614
 Stein A, Radhakrishnan A, Riedel D, Fasshauer D, Jahn R. Synaptotagmin activates membrane fusion through a Ca2+-dependent trans interaction with phospholipids. Nature Structural & Molecular Biology. 2007 Sep 23;14(10):904–11. doi: 10.1038/nsmb1305.; Martens S, Kozlov MM, McMahon HT. How synaptotagmin promotes membrane fusion. Science. 2007 May 25;316(5828):1205–8. doi: 10.1126/science.1142614. PMID: 17478680.; Barclay JW, Craig TJ, Fisher RJ, Ciufo LF, Evans GJO, Morgan A, Burgoyne RD. Phosphorylation of Munc18 by Protein Kinase C Regulates the Kinetics of Exocytosis. Journal of Biological Chemistry. 2003 Mar;278(12):10538–45. doi: 10.1074/jbc.m211114200.
Norepinephrine Neurotransmitter Release Cycle

Accession ID: Reactome:R-GGA-181430
  • 10.1038/nsmb1305
  • 10.1074/jbc.m211114200
  • 10.1126/science.1142614
 Stein A, Radhakrishnan A, Riedel D, Fasshauer D, Jahn R. Synaptotagmin activates membrane fusion through a Ca2+-dependent trans interaction with phospholipids. Nature Structural & Molecular Biology. 2007 Sep 23;14(10):904–11. doi: 10.1038/nsmb1305.; Martens S, Kozlov MM, McMahon HT. How synaptotagmin promotes membrane fusion. Science. 2007 May 25;316(5828):1205–8. doi: 10.1126/science.1142614. PMID: 17478680.; Barclay JW, Craig TJ, Fisher RJ, Ciufo LF, Evans GJO, Morgan A, Burgoyne RD. Phosphorylation of Munc18 by Protein Kinase C Regulates the Kinetics of Exocytosis. Journal of Biological Chemistry. 2003 Mar;278(12):10538–45. doi: 10.1074/jbc.m211114200.
Transmission across Chemical Synapses

Accession ID: Reactome:R-HSA-112315		 -
Norepinephrine Neurotransmitter Release Cycle

Accession ID: Reactome:R-MMU-181430
  • 10.1038/nsmb1305
  • 10.1074/jbc.m211114200
  • 10.1126/science.1142614
 Stein A, Radhakrishnan A, Riedel D, Fasshauer D, Jahn R. Synaptotagmin activates membrane fusion through a Ca2+-dependent trans interaction with phospholipids. Nature Structural & Molecular Biology. 2007 Sep 23;14(10):904–11. doi: 10.1038/nsmb1305.; Martens S, Kozlov MM, McMahon HT. How synaptotagmin promotes membrane fusion. Science. 2007 May 25;316(5828):1205–8. doi: 10.1126/science.1142614. PMID: 17478680.; Barclay JW, Craig TJ, Fisher RJ, Ciufo LF, Evans GJO, Morgan A, Burgoyne RD. Phosphorylation of Munc18 by Protein Kinase C Regulates the Kinetics of Exocytosis. Journal of Biological Chemistry. 2003 Mar;278(12):10538–45. doi: 10.1074/jbc.m211114200.
Neuronal System

Accession ID: Reactome:R-RNO-112316		 -
Transmission across Chemical Synapses

Accession ID: Reactome:R-SSC-112315		 -
Neurotransmitter release cycle

Accession ID: Reactome:R-XTR-112310
  • 10.1007/s00441-006-0243-z
  • 10.1007/s00441-006-0244-y
  • 10.1016/j.neuron.2007.09.001
  • 10.1146/annurev.neuro.26.041002.131412
 Edwards RH. The neurotransmitter cycle and quantal size. Neuron. 2007 Sep 20;55(6):835–58. doi: 10.1016/j.neuron.2007.09.001. PMID: 17880890.; Schoch S, Gundelfinger ED. Molecular organization of the presynaptic active zone. Cell Tissue Res. 2006 Nov;326(2):379–91. doi: 10.1007/s00441-006-0244-y. PMID: 16865347.; Becherer U, Rettig J. Vesicle pools, docking, priming, and release. Cell Tissue Res. 2006 Nov;326(2):393–407. doi: 10.1007/s00441-006-0243-z. PMID: 16819626.; Sudhof TC. The synaptic vesicle cycle. Annu Rev Neurosci. 2004;27():509–47. doi: 10.1146/annurev.neuro.26.041002.131412. PMID: 15217342.
Neuronal System

Accession ID: Reactome:R-BTA-112316		 -
Norepinephrine Neurotransmitter Release Cycle

Accession ID: Reactome:R-CFA-181430
  • 10.1038/nsmb1305
  • 10.1074/jbc.m211114200
  • 10.1126/science.1142614
 Stein A, Radhakrishnan A, Riedel D, Fasshauer D, Jahn R. Synaptotagmin activates membrane fusion through a Ca2+-dependent trans interaction with phospholipids. Nature Structural & Molecular Biology. 2007 Sep 23;14(10):904–11. doi: 10.1038/nsmb1305.; Martens S, Kozlov MM, McMahon HT. How synaptotagmin promotes membrane fusion. Science. 2007 May 25;316(5828):1205–8. doi: 10.1126/science.1142614. PMID: 17478680.; Barclay JW, Craig TJ, Fisher RJ, Ciufo LF, Evans GJO, Morgan A, Burgoyne RD. Phosphorylation of Munc18 by Protein Kinase C Regulates the Kinetics of Exocytosis. Journal of Biological Chemistry. 2003 Mar;278(12):10538–45. doi: 10.1074/jbc.m211114200.
Norepinephrine Neurotransmitter Release Cycle

Accession ID: Reactome:R-DRE-181430
  • 10.1038/nsmb1305
  • 10.1074/jbc.m211114200
  • 10.1126/science.1142614
 Stein A, Radhakrishnan A, Riedel D, Fasshauer D, Jahn R. Synaptotagmin activates membrane fusion through a Ca2+-dependent trans interaction with phospholipids. Nature Structural & Molecular Biology. 2007 Sep 23;14(10):904–11. doi: 10.1038/nsmb1305.; Martens S, Kozlov MM, McMahon HT. How synaptotagmin promotes membrane fusion. Science. 2007 May 25;316(5828):1205–8. doi: 10.1126/science.1142614. PMID: 17478680.; Barclay JW, Craig TJ, Fisher RJ, Ciufo LF, Evans GJO, Morgan A, Burgoyne RD. Phosphorylation of Munc18 by Protein Kinase C Regulates the Kinetics of Exocytosis. Journal of Biological Chemistry. 2003 Mar;278(12):10538–45. doi: 10.1074/jbc.m211114200.
Neurotransmitter release cycle

Accession ID: Reactome:R-DDI-112310
  • 10.1007/s00441-006-0243-z
  • 10.1007/s00441-006-0244-y
  • 10.1016/j.neuron.2007.09.001
  • 10.1146/annurev.neuro.26.041002.131412
 Edwards RH. The neurotransmitter cycle and quantal size. Neuron. 2007 Sep 20;55(6):835–58. doi: 10.1016/j.neuron.2007.09.001. PMID: 17880890.; Schoch S, Gundelfinger ED. Molecular organization of the presynaptic active zone. Cell Tissue Res. 2006 Nov;326(2):379–91. doi: 10.1007/s00441-006-0244-y. PMID: 16865347.; Becherer U, Rettig J. Vesicle pools, docking, priming, and release. Cell Tissue Res. 2006 Nov;326(2):393–407. doi: 10.1007/s00441-006-0243-z. PMID: 16819626.; Sudhof TC. The synaptic vesicle cycle. Annu Rev Neurosci. 2004;27():509–47. doi: 10.1146/annurev.neuro.26.041002.131412. PMID: 15217342.
Neurotransmitter release cycle

Accession ID: Reactome:R-GGA-112310
  • 10.1007/s00441-006-0243-z
  • 10.1007/s00441-006-0244-y
  • 10.1016/j.neuron.2007.09.001
  • 10.1146/annurev.neuro.26.041002.131412
 Edwards RH. The neurotransmitter cycle and quantal size. Neuron. 2007 Sep 20;55(6):835–58. doi: 10.1016/j.neuron.2007.09.001. PMID: 17880890.; Schoch S, Gundelfinger ED. Molecular organization of the presynaptic active zone. Cell Tissue Res. 2006 Nov;326(2):379–91. doi: 10.1007/s00441-006-0244-y. PMID: 16865347.; Becherer U, Rettig J. Vesicle pools, docking, priming, and release. Cell Tissue Res. 2006 Nov;326(2):393–407. doi: 10.1007/s00441-006-0243-z. PMID: 16819626.; Sudhof TC. The synaptic vesicle cycle. Annu Rev Neurosci. 2004;27():509–47. doi: 10.1146/annurev.neuro.26.041002.131412. PMID: 15217342.
Norepinephrine Neurotransmitter Release Cycle

Accession ID: Reactome:R-HSA-181430
  • 10.1038/nsmb1305
  • 10.1074/jbc.m211114200
  • 10.1126/science.1142614
 Stein A, Radhakrishnan A, Riedel D, Fasshauer D, Jahn R. Synaptotagmin activates membrane fusion through a Ca2+-dependent trans interaction with phospholipids. Nature Structural & Molecular Biology. 2007 Sep 23;14(10):904–11. doi: 10.1038/nsmb1305.; Martens S, Kozlov MM, McMahon HT. How synaptotagmin promotes membrane fusion. Science. 2007 May 25;316(5828):1205–8. doi: 10.1126/science.1142614. PMID: 17478680.; Barclay JW, Craig TJ, Fisher RJ, Ciufo LF, Evans GJO, Morgan A, Burgoyne RD. Phosphorylation of Munc18 by Protein Kinase C Regulates the Kinetics of Exocytosis. Journal of Biological Chemistry. 2003 Mar;278(12):10538–45. doi: 10.1074/jbc.m211114200.
Neurotransmitter release cycle

Accession ID: Reactome:R-MMU-112310
  • 10.1007/s00441-006-0243-z
  • 10.1007/s00441-006-0244-y
  • 10.1016/j.neuron.2007.09.001
  • 10.1146/annurev.neuro.26.041002.131412
 Edwards RH. The neurotransmitter cycle and quantal size. Neuron. 2007 Sep 20;55(6):835–58. doi: 10.1016/j.neuron.2007.09.001. PMID: 17880890.; Schoch S, Gundelfinger ED. Molecular organization of the presynaptic active zone. Cell Tissue Res. 2006 Nov;326(2):379–91. doi: 10.1007/s00441-006-0244-y. PMID: 16865347.; Becherer U, Rettig J. Vesicle pools, docking, priming, and release. Cell Tissue Res. 2006 Nov;326(2):393–407. doi: 10.1007/s00441-006-0243-z. PMID: 16819626.; Sudhof TC. The synaptic vesicle cycle. Annu Rev Neurosci. 2004;27():509–47. doi: 10.1146/annurev.neuro.26.041002.131412. PMID: 15217342.
Transmission across Chemical Synapses

Accession ID: Reactome:R-RNO-112315		 -
Norepinephrine Neurotransmitter Release Cycle

Accession ID: Reactome:R-SSC-181430
  • 10.1038/nsmb1305
  • 10.1074/jbc.m211114200
  • 10.1126/science.1142614
 Stein A, Radhakrishnan A, Riedel D, Fasshauer D, Jahn R. Synaptotagmin activates membrane fusion through a Ca2+-dependent trans interaction with phospholipids. Nature Structural & Molecular Biology. 2007 Sep 23;14(10):904–11. doi: 10.1038/nsmb1305.; Martens S, Kozlov MM, McMahon HT. How synaptotagmin promotes membrane fusion. Science. 2007 May 25;316(5828):1205–8. doi: 10.1126/science.1142614. PMID: 17478680.; Barclay JW, Craig TJ, Fisher RJ, Ciufo LF, Evans GJO, Morgan A, Burgoyne RD. Phosphorylation of Munc18 by Protein Kinase C Regulates the Kinetics of Exocytosis. Journal of Biological Chemistry. 2003 Mar;278(12):10538–45. doi: 10.1074/jbc.m211114200.