Pathways Knowlegdes

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Pathway DOIs Note
superpathway of nicotinate degradation

Accession ID: BioCyc:META_PWY-5062
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nicotine degradation II (pyrrolidine pathway)

Accession ID: BioCyc:META_PWY-6993
  • 10.1128/aem.02300-08
  • 10.1128/aem.02529-07
Tang H, Wang L, Meng X, Ma L, Wang S, He X, Wu G, Xu P. Novel nicotine oxidoreductase-encoding gene involved in nicotine degradation by Pseudomonas putida strain S16. Appl Environ Microbiol. 2009 Feb;75(3):772–8. PMID: 19060159; PMCID: PMC2632140.; Tang H, Wang S, Ma L, Meng X, Deng Z, Zhang D, Ma C, Xu P. A novel gene, encoding 6-hydroxy-3-succinoylpyridine hydroxylase, involved in nicotine degradation by Pseudomonas putida strain S16. Appl Environ Microbiol. 2008 Mar;74(5):1567–74. PMID: 18203859; PMCID: PMC2258644.
nicotinate degradation I

Accession ID: BioCyc:META_PWY-722
  • 10.1016/s0021-9258(18)70671-6
  • 10.1073/pnas.0802273105
Jiménez JI, Canales Á, Jiménez-Barbero J, Ginalski K, Rychlewski L, García JL, Díaz E. Deciphering the genetic determinants for aerobic nicotinic acid degradation: The nic cluster from Pseudomonas putida KT2440. Proc. Natl. Acad. Sci. U.S.A. 2008 Aug 12;105(32):11329–34. doi: 10.1073/pnas.0802273105.; Behrman EJ, Stanier RY. THE BACTERIAL OXIDATION OF NICOTINIC ACID. Journal of Biological Chemistry. 1957 Oct;228(2):923–45. doi: 10.1016/s0021-9258(18)70671-6.
nicotine degradation III (VPP pathway)

Accession ID: BioCyc:META_PWY-7128
  • 10.1007/s00253-012-4007-2
  • 10.1128/aem.02265-14
Yu H, Tang H, Zhu X, Li Y, Xu P. Molecular Mechanism of Nicotine Degradation by a Newly Isolated Strain, Ochrobactrum sp. Strain SJY1. Appl Environ Microbiol. 2015 Jan;81(1):272–81. doi: 10.1128/aem.02265-14.; Wang S, Huang H, Xie K, Xu P. Identification of nicotine biotransformation intermediates by Agrobacterium tumefaciens strain S33 suggests a novel nicotine degradation pathway. Applied Microbiology and Biotechnology. 2012 Apr 01;95(6):1567–78. doi: 10.1007/s00253-012-4007-2.