dTDP-L-rhamnose biosynthesis

Kaminski L, Eichler J. Haloferax volcanii N-Glycosylation: Delineating the Pathway of dTDP-rhamnose Biosynthesis. PLoS ONE. 2014 May 15;9(5):e97441. doi: 10.1371/journal.pone.0097441.; Madduri K, Waldron C, Merlo DJ. Rhamnose Biosynthesis Pathway Supplies Precursors for Primary and Secondary Metabolism in Saccharopolyspora spinosa. J Bacteriol. 2001 Oct;183(19):5632–8. doi: 10.1128/jb.183.19.5632-5638.2001.; Giraud MF, Naismith JH. The rhamnose pathway. Curr Opin Struct Biol. 2000 Dec;10(6):687–96. doi: 10.1016/s0959-440x(00)00145-7. PMID: 11114506.

Metabolites

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

dTDP-alpha-D-glucose

Formula: C16H24N2O16P2 (562.0601044)

CAS ID:

NADPH(4-)

Formula: C21H26N7O17P3 (741.0598016)

CAS ID: 53-57-6

NADP(3-)

Formula: C21H25N7O17P3 (740.051977)

CAS ID: 53-59-8



Enzyme

EC Number name full name note
1.1.1.133 dTDP-4-dehydrorhamnose reductase dTDP-6-deoxy-beta-L-mannose:NADP+ 4-oxidoreductase
5.1.3.13 dTDP-4-dehydrorhamnose 3,5-epimerase dTDP-4-dehydro-6-deoxy-D-glucose 3,5-epimerase


Proteins

Protein ID name full name