guanosine ribonucleotides de novo biosynthesis

Metabolites

Diphosphate

Formula: H4P2O7 (177.9432294)

CAS ID: 2466-09-3

Guanosine

Formula: C10H13N5O5 (283.09166480000005)

CAS ID: 118-00-3

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Magnesium cation

Formula: Mg (23.98505)

CAS ID: 22537-22-0

Potassium cation

Formula: K (38.963708)

CAS ID: 24203-36-9

Rubidium cation

Formula: Rb (84.9118)

CAS ID: 22537-38-8

3-bromopyruvate

Formula: C3H2BrO3 (164.9187302)

CAS ID: 68-38-2

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:

NAD(1-)

Formula: C21H26N7O14P2 (662.1012936000001)

CAS ID: 53-84-9

ADP(3-)

Formula: C10H12N5O10P2 (424.0059412)

CAS ID:



Enzyme

EC Number name full name note
1.1.1.205 IMP dehydrogenase IMP:NAD+ oxidoreductase
2.7.4.3 adenylate kinase ATP:AMP phosphotransferase
2.7.4.6 nucleoside-diphosphate kinase ATP:nucleoside-diphosphate phosphotransferase
2.7.4.8 guanylate kinase ATP:(d)GMP phosphotransferase
6.3.5.2 GMP synthase (glutamine-hydrolysing) xanthosine-5'-phosphate:L-glutamine amido-ligase (AMP-forming)


Proteins

Protein ID name full name
P04079 guaA GMP synthase [glutamine-hydrolyzing]
P0A763 ndk Nucleoside diphosphate kinase
P0ADG7 guaB Inosine-5'-monophosphate dehydrogenase
P60546 gmk Guanylate kinase
P69441 adk Adenylate kinase