spermine and spermidine degradation I

Wanders RJ, Waterham HR. Biochemistry of mammalian peroxisomes revisited. Annu Rev Biochem. 2006;75():295–332. doi: 10.1146/annurev.biochem.74.082803.133329. PMID: 16756494.; Wallace HM, Fraser AV, Hughes A. A perspective of polyamine metabolism. Biochem J. 2003 Nov 15;376(Pt 1):1–14. PMID: 13678416; PMCID: PMC1223767.

Metabolites

3-Acetamidopropanal

Formula: C5H9NO2 (115.0633254)

CAS ID: 73323-68-9

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Hydrogen peroxide

Formula: H2O2 (34.0054792)

CAS ID: 7722-84-1

Oxygen

Formula: O2 (31.98983)

CAS ID: 7782-44-7

3-amino-propanal

Formula: C3H8NO (74.0605858)

CAS ID:

N(1)-acetylsperminium(3+)

Formula: C12H31N4O (247.24977359999997)

CAS ID:

N1,N11-Bis(ethyl)norspermine

Formula: C13H32N4 (244.2626832)

CAS ID: 121749-39-1

MDL-72527 free base

Formula: C12H20N2 (192.16264)

CAS ID: 99207-33-7



Enzyme

EC Number name full name note
1.5.3.13 N1-acetylpolyamine oxidase N1-acetylpolyamine:oxygen oxidoreductase (3-acetamidopropanal-forming)
1.5.3.16 spermine oxidase spermidine:oxygen oxidoreductase (spermidine-forming)
2.3.1.57 diamine N-acetyltransferase acetyl-CoA:alkane-alpha,omega-diamine N-acetyltransferase


Proteins

Protein ID name full name