superpathway of isoflavonoids (via naringenin)

Akashi T, Aoki T, Ayabe S. Molecular and biochemical characterization of 2-hydroxyisoflavanone dehydratase. Involvement of carboxylesterase-like proteins in leguminous isoflavone biosynthesis. Plant Physiol. 2005 Mar;137(3):882–91. PMID: 15734910; PMCID: PMC1065389.; Yenesew A, Midiwo JO, Heydenreich M, Schanzenbach D, Peter MG. Two isoflavanones from the stem bark of Erythrina sacleuxii. Phytochemistry. 2000 Nov;55(5):457–9. doi: 10.1016/s0031-9422(00)00349-6. PMID: 11140607.; Akashi T, Aoki T, Ayabe S. CYP81E1, a Cytochrome P450 cDNA of Licorice (Glycyrrhiza echinataL.), Encodes Isoflavone 2'-Hydroxylase. Biochemical and Biophysical Research Communications. 1998 Oct;251(1):67–70. doi: 10.1006/bbrc.1998.9414.; KOCHS G, GRISEBACH H. Enzymic synthesis of isoflavones. European Journal of Biochemistry. 1986 Mar;155(2):311–8. doi: 10.1111/j.1432-1033.1986.tb09492.x.; Robbins MP, Bolwell GP, Dixon RA. Metabolic changes in elicitor-treated bean cells. Selectivity of enzyme induction in relation to phytoalexin accumulation. Eur J Biochem. 1985 May 02;148(3):563–9. doi: 10.1111/j.1432-1033.1985.tb08877.x. PMID: 3996394.; WENGENMAYER H, EBEL J, GRISEBACH H. Purification and Properties of a S-Adenosylmethionine: Isoflavone 4'-O-Methyltransferase from Cell Suspension Cultures of Cicer arietinum L. European Journal of Biochemistry. 1974 Dec;50(1):135–43. doi: 10.1111/j.1432-1033.1974.tb03881.x.

Metabolites

Ancymidol

Formula: C15H16N2O2 (256.12117159999997)

CAS ID: 12771-68-5

CO2

Formula: CO2 (43.98983)

CAS ID: 124-38-9

Diphosphate

Formula: H4P2O7 (177.9432294)

CAS ID: 2466-09-3

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Juglone

Formula: C10H6O3 (174.03169259999999)

CAS ID: 481-39-0

Naringenin

Formula: C15H12O5 (272.0684702)

CAS ID: 480-41-1

Oxygen

Formula: O2 (31.98983)

CAS ID: 7782-44-7

Prunetin

Formula: C16H12O5 (284.0684702)

CAS ID: 552-59-0

Ketoconazole

Formula: C26H28Cl2N4O4 (530.1487508)

CAS ID: 65277-42-1

2-oxoglutarate(2-)

Formula: C5H4O5 (144.00587339999998)

CAS ID: 64-15-3

succinate(2-)

Formula: C4H4O4 (116.01095839999999)

CAS ID: 56-14-4

NADPH(4-)

Formula: C21H26N7O17P3 (741.0598016)

CAS ID: 53-57-6

NADP(3-)

Formula: C21H25N7O17P3 (740.051977)

CAS ID: 53-59-8

tetcyclacis

Formula: C13H12N5Cl1 (273.0781182)

CAS ID: 65245-23-0



Enzyme

EC Number name full name note


Proteins

Protein ID name full name