hydrogen sulfide biosynthesis II (mammalian)

Singh S, Padovani D, Leslie RA, Chiku T, Banerjee R. Relative Contributions of Cystathionine ß-Synthase and ?-Cystathionase to H2S Biogenesis via Alternative Trans-sulfuration Reactions. Journal of Biological Chemistry. 2009 Aug;284(33):22457–66. doi: 10.1074/jbc.m109.010868.

Metabolites

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Hydrogen sulfide

Formula: H2S (33.9877212)

CAS ID: 7783-06-4

pyruvate

Formula: C3H3O3 (87.00821880000001)

CAS ID: 57-60-3

2-oxobutanoate

Formula: C4H5O3 (101.02386800000001)

CAS ID:

pyridoxal 5'-phosphate(2-)

Formula: C8H8NO6P (245.0089238)

CAS ID:



Enzyme

EC Number name full name note
4.2.1.22 cystathionine beta-synthase L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)
4.4.1.1 cystathionine gamma-lyase L-cystathionine cysteine-lyase (deaminating; 2-oxobutanoate-forming)
4.4.1.2 homocysteine desulfhydrase L-homocysteine hydrogen-sulfide-lyase (deaminating; 2-oxobutanoate-forming)


Proteins

Protein ID name full name