biotin-carboxyl carrier protein assembly

Tissot G, Pepin R, Job D, Douce R, Alban C. Purification and properties of the chloroplastic form of biotin holocarboxylase synthetase from Arabidopsis thaliana overexpressed in Escherichia coli. European Journal of Biochemistry. 1998 Dec;258(2):586–96. doi: 10.1046/j.1432-1327.1998.2580586.x.; Sun J, Ke J, Johnson JL, Nikolau BJ, Wurtele ES. Biochemical and molecular biological characterization of CAC2, the Arabidopsis thaliana gene coding for the biotin carboxylase subunit of the plastidic acetyl-coenzyme A carboxylase. Plant Physiol. 1997 Dec;115(4):1371–83. PMID: 9414551; PMCID: PMC158602.; Amrein R, Güntert TW, Dingemanse J, Lorscheid T, Stabl M, Schmid-Burgk W. Interactions of moclobemide with concomitantly administered medication: evidence from pharmacological and clinical studies. Psychopharmacology (Berl). 1992;106 Suppl():S24–31. doi: 10.1007/bf02246229. PMID: 1546135.

Metabolites

ADP

Formula: C10H15N5O10P2 (427.02941500000003)

CAS ID: 58-64-0

Diphosphate

Formula: H4P2O7 (177.9432294)

CAS ID: 2466-09-3

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

HCO3-

Formula: HCO3 (60.9925696)

CAS ID: 71-52-3

biotinate

Formula: C10H15N2O3S (243.080334)

CAS ID:

adenosine 5'-monophosphate(2-)

Formula: C10H12N5O7P (345.0474332)

CAS ID:

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:



Enzyme

EC Number name full name note
6.3.4.-
6.3.4.11 biotin-[methylcrotonoyl-CoA-carboxylase] ligase biotin:apo-[3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)] ligase (AMP-forming)
6.3.4.14 biotin carboxylase [biotin carboxyl-carrier protein]-biotin-N6-L-lysine:hydrogencarbonate ligase (ADP-forming)
6.3.4.15 biotin-[biotin carboxyl-carrier protein] ligase biotin:apo-[carboxyl-carrier protein] ligase (AMP-forming)
6.4.1.2 acetyl-CoA carboxylase acetyl-CoA:hydrogencarbonate ligase (ADP-forming)


Proteins

Protein ID name full name