pyruvate decarboxylation to acetyl CoA

Metabolites

CO2

Formula: CO2 (43.98983)

CAS ID: 124-38-9

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

pyruvate

Formula: C3H3O3 (87.00821880000001)

CAS ID: 57-60-3

thiamine(1+) diphosphate(3-)

Formula: C12H16N4O7P2S (422.0214926)

CAS ID:

NADH(2-)

Formula: C21H27N7O14P2 (663.1091182000001)

CAS ID:

NAD(1-)

Formula: C21H26N7O14P2 (662.1012936000001)

CAS ID: 53-84-9



Enzyme

EC Number name full name note
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring) pyruvate:[dihydrolipoyllysine-residue acetyltransferase]-lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-acetylating)
1.8.1.4 dihydrolipoyl dehydrogenase protein-N6-(dihydrolipoyl)lysine:NAD+ oxidoreductase
2.3.1.12 dihydrolipoyllysine-residue acetyltransferase acetyl-CoA:enzyme N6-(dihydrolipoyl)lysine S-acetyltransferase


Proteins

Protein ID name full name
Q8NNF6 aceE PYRUVATE DEHYDROGENASE E1 COMPONENT
Q8NNJ2 sucB DIHYDROLIPOAMIDE SUCCINYLTRANSFERASE
Q8NTE1 lpd DIHYDROLIPOAMIDE DEHYDROGENASE