UDP-α-D-xylose biosynthesis

Gu X, Lee SG, Bar-Peled M. Biosynthesis of UDP-xylose and UDP-arabinose in Sinorhizobium meliloti 1021: first characterization of a bacterial UDP-xylose synthase, and UDP-xylose 4-epimerase. Microbiology (Reading). 2011 Jan;157(Pt 1):260–9. PMID: 20847005; PMCID: PMC3068629.; Pattathil S, Harper AD, Bar-Peled M. Biosynthesis of UDP-xylose: characterization of membrane-bound AtUxs2. Planta. 2005 Jun;221(4):538–48. doi: 10.1007/s00425-004-1471-7. PMID: 15655675.; Bindschedler LV, Wheatley E, Gay E, Cole J, Cottage A, Bolwell GP. Characterisation and expression of the pathway from UDP-glucose to UDP-xylose in differentiating tobacco tissue. Plant Mol Biol. 2005 Jan;57(2):285–301. doi: 10.1007/s11103-004-7795-7. PMID: 15821883.; Harper AD, Bar-Peled M. Biosynthesis of UDP-xylose. Cloning and characterization of a novel Arabidopsis gene family, UXS, encoding soluble and putative membrane-bound UDP-glucuronic acid decarboxylase isoforms. Plant Physiol. 2002 Dec;130(4):2188–98. PMID: 12481102; PMCID: PMC166730.

Metabolites

Ammonium chloride

Formula: NH4Cl (53.003225400000005)

CAS ID: 12125-02-9

Calcium cation

Formula: Ca (39.962591)

CAS ID: 14127-61-8

CO2

Formula: CO2 (43.98983)

CAS ID: 124-38-9

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Magnesium cation

Formula: Mg (23.98505)

CAS ID: 22537-22-0

Manganese(2+)

Formula: Mn (54.938046)

CAS ID: 7439-96-5

Potassium chloride

Formula: ClK (73.93256099999999)

CAS ID: 7447-40-7

ammonium sulfate

Formula: H8N2O4S (132.0204768)

CAS ID: 7783-20-2

NAD(1-)

Formula: C21H26N7O14P2 (662.1012936000001)

CAS ID: 53-84-9

UDP(3-)

Formula: C9H11N2O12P2 (400.9787246)

CAS ID: 86527-70-0

dTDP(3-)

Formula: C10H13N2O11P2 (398.9994588)

CAS ID:

dTMP(2-)

Formula: C10H13N2O8P (320.0409508)

CAS ID: 14057-65-9



Enzyme

EC Number name full name note
1.1.1.22 UDP-glucose 6-dehydrogenase UDP-alpha-D-glucose:NAD+ 6-oxidoreductase
4.1.1.35 UDP-glucuronate decarboxylase UDP-D-glucuronate carboxy-lyase (UDP-D-xylose-forming)


Proteins

Protein ID name full name