superpathway of tetrahydrofolate biosynthesis and salvage
Metabolites
Enzyme
| EC Number | name | full name | note |
|---|---|---|---|
| 1.5.1.5 | methylenetetrahydrofolate dehydrogenase (NADP+) | 5,10-methylenetetrahydrofolate:NADP+ oxidoreductase | |
| 3.5.1.2 | glutaminase | L-glutamine amidohydrolase | |
| 3.5.4.16 | GTP cyclohydrolase I | GTP 7,8-8,9-dihydrolase | |
| 3.5.4.9 | methenyltetrahydrofolate cyclohydrolase | 5,10-methenyltetrahydrofolate 5-hydrolase (decyclizing) | |
| 4.3.2.10 | imidazole glycerol-phosphate synthase | 5-[(5-phospho-1-deoxy-D-ribulos-1-ylamino)methylideneamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate-lyase (L-glutamine-hydrolysing; 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide-forming) |
Proteins
| Protein ID | name | full name |
|---|---|---|
| P58788 | hisH | Imidazole glycerol phosphate synthase subunit HisH |
| Q8UEK8 | folE | GTP cyclohydrolase 1 |
| Q8UHU0 | folD | Bifunctional protein FolD |