pyridoxal 5'-phosphate salvage I

Roje S. Vitamin B biosynthesis in plants. Phytochemistry. 2007 Jul;68(14):1904–21. doi: 10.1016/j.phytochem.2007.03.038. PMID: 17512961.; Sang Y, Barbosa JM, Wu H, Locy RD, Singh NK: Identification of a pyridoxine (pyridoxamine) 5'-phosphate oxidase from Arabidopsis thaliana. FEBS Lett. 2007 Feb 6;581(3):344-8. doi: 10.1016/j.febslet.2006.12.028. Epub 2007 Jan 3.; Tambasco-Studart M, Titiz O, Raschle T, Forster G, Amrhein N, Fitzpatrick TB: Vitamin B6 biosynthesis in higher plants. Proc Natl Acad Sci U S A. 2005 Sep 20;102(38):13687-92. doi: 10.1073/pnas.0506228102. Epub 2005 Sep 12.; Tanaka T, Tateno Y, Gojobori T. Evolution of vitamin B6 (pyridoxine) metabolism by gain and loss of genes. Mol Biol Evol. 2005 Feb;22(2):243–50. doi: 10.1093/molbev/msi011. PMID: 15483325.; Lum HK, Kwok F, Lo SC. Cloning and characterization of Arabidopsis thaliana pyridoxal kinase. Planta. 2002 Sep;215(5):870–9. doi: 10.1007/s00425-002-0799-0. PMID: 12244454.; Shi H, Zhu JK. SOS4, a pyridoxal kinase gene, is required for root hair development in Arabidopsis. Plant Physiol. 2002 Jun;129(2):585–93. PMID: 12068103; PMCID: PMC161684.; Shi H, Xiong L, Stevenson B, Lu T, Zhu JK. The Arabidopsis salt overly sensitive 4 mutants uncover a critical role for vitamin B6 in plant salt tolerance. Plant Cell. 2002 Mar;14(3):575–88. PMID: 11910005; PMCID: PMC150580.; Bilski P, Li MY, Ehrenshaft M, Daub ME, Chignell CF. Vitamin B6 (pyridoxine) and its derivatives are efficient singlet oxygen quenchers and potential fungal antioxidants. Photochem Photobiol. 2000 Feb;71(2):129–34. doi: 10.1562/0031-8655(2000)071<0129:sipvbp>2.0.co;2. PMID: 10687384.; McCormick DB, Chen H. Update on Interconversions of Vitamin B-6 with Its Coenzyme. The Journal of Nutrition. 1999 Feb;129(2):325–7. doi: 10.1093/jn/129.2.325.; MEISTER A. On the Transamination of Enzymes. Annals of the New York Academy of Sciences. 1990 May;585(1):13–31. doi: 10.1111/j.1749-6632.1990.tb28038.x.; Tsuge H, Kuroda Y, Iwamoto A, Ohashi K. Partial purification and property of pyridoxine (pyridoxamine)-5'-phosphate oxidase isozymes from wheat seedlings. Archives of Biochemistry and Biophysics. 1982 Sep;217(2):479–84. doi: 10.1016/0003-9861(82)90527-6.

Metabolites

ADP

Formula: C10H15N5O10P2 (427.02941500000003)

CAS ID: 58-64-0

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Hydrogen peroxide

Formula: H2O2 (34.0054792)

CAS ID: 7722-84-1

Oxygen

Formula: O2 (31.98983)

CAS ID: 7782-44-7

Pyridoxal

Formula: C8H9NO3 (167.0582404)

CAS ID: 66-72-8

Pyridoxine

Formula: C8H11NO3 (169.0738896)

CAS ID: 65-23-6

Zinc cation

Formula: Zn (63.929145)

CAS ID: 23713-49-7

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:



Enzyme

EC Number name full name note
1.4.3.5 pyridoxal 5'-phosphate synthase pyridoxamine-5'-phosphate:oxygen oxidoreductase (deaminating)
5.1.99.6 NAD(P)H-hydrate epimerase (6R)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide 6-epimerase


Proteins

Protein ID name full name