superpathway of bitter acids biosynthesis
Goese M, Kammhuber K, Bacher A, Zenk MH, Eisenreich W. Biosynthesis of bitter acids in hops. A (13)C-NMR and (2)H-NMR study on the building blocks of humulone. Eur J Biochem. 1999 Jul;263(2):447–54. doi: 10.1046/j.1432-1327.1999.00518.x. PMID: 10406953.; Paniego NB, Zuurbier KWM, Fung S, van der Heijden R, Scheffer JJC, Verpoorte R. Phlorisovalerophenone synthase, a novel polyketide synthase from hop (Humulus lupulus L.) cones. European Journal of Biochemistry. 1999 Jun;262(2):612–6. doi: 10.1046/j.1432-1327.1999.00444.x.
Metabolites
2-Methyl-1-[2,4,6-trihydroxy-3-(3-methyl-2-butenyl)phenyl]-1-propanone
Formula: C15H20O4 (264.13615200000004)
CAS ID: 35932-36-6
Enzyme
| EC Number | name | full name | note |
|---|---|---|---|
| 6.2.1.- | |||
| 2.3.1.156 | phloroisovalerophenone synthase | isovaleryl-CoA:malonyl-CoA acyltransferase | |
| 2.3.1.74 | chalcone synthase | malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing) | |
| 2.5.1.136 | 2-acylphloroglucinol 4-prenyltransferase | prenyl-diphosphate:2-acylphloroglucinol 4-prenyltransferase | |
| 2.5.1.137 | 2-acyl-4-prenylphloroglucinol 6-prenyltransferase | dimethylallyl-diphosphate:2-acyl-4-prenylphloroglucinol 6-dimethylallyltransferase | |
| 6.2.1.17 | propionate-CoA ligase | propanoate:CoA ligase (AMP-forming) |
Proteins
| Protein ID | name | full name |
|---|