geranylgeranyl diphosphate biosynthesis

Rodríguez-Concepción M, Boronat A. Elucidation of the methylerythritol phosphate pathway for isoprenoid biosynthesis in bacteria and plastids. A metabolic milestone achieved through genomics. Plant Physiol. 2002 Nov;130(3):1079–89. PMID: 12427975; PMCID: PMC1540259.; Okada K, Saito T, Nakagawa T, Kawamukai M, Kamiya Y. Five geranylgeranyl diphosphate synthases expressed in different organs are localized into three subcellular compartments in Arabidopsis. Plant Physiol. 2000 Apr;122(4):1045–56. PMID: 10759500; PMCID: PMC58939.

Metabolites

Diphosphate

Formula: H4P2O7 (177.9432294)

CAS ID: 2466-09-3

Magnesium cation

Formula: Mg (23.98505)

CAS ID: 22537-22-0

Manganese(2+)

Formula: Mn (54.938046)

CAS ID: 7439-96-5

2-trans,6-trans,10-trans-geranylgeranyl diphosphate(3-)

Formula: C20H33O7P2 (447.1701428)

CAS ID:

isopentenyl diphosphate(3-)

Formula: C5H9O7P2 (242.9823524)

CAS ID:



Enzyme

EC Number name full name note
2.5.1.-
2.5.1.1 dimethylallyltranstransferase prenyl-diphosphate:3-methylbut-3-en-1-yl-diphosphate prenyltranstransferase
2.5.1.10 (2E,6E)-farnesyl diphosphate synthase geranyl-diphosphate:isopentenyl-diphosphate geranyltranstransferase
2.5.1.29 geranylgeranyl diphosphate synthase (2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase


Proteins

Protein ID name full name
P17060 crtE Geranylgeranyl diphosphate synthase
P22873 crtE Geranylgeranyl diphosphate synthase
Q12051 BTS1 Geranylgeranyl pyrophosphate synthase BTS1
Q53479 idsA Short chain isoprenyl diphosphate synthase