anhydromuropeptides recycling I

Johnson JW, Fisher JF, Mobashery S. Bacterial cell-wall recycling. Annals of the New York Academy of Sciences. 2012 Nov 16;1277(1):54–75. doi: 10.1111/j.1749-6632.2012.06813.x.; Park JT, Uehara T. How bacteria consume their own exoskeletons (turnover and recycling of cell wall peptidoglycan). Microbiol Mol Biol Rev. 2008 Jun;72(2):211–27, table of contents. PMID: 18535144; PMCID: PMC2415748.

Metabolites

D-Glucosamine 6-phosphate

Formula: C6H14NO8P (259.04570140000004)

CAS ID: 3616-42-0

Diphosphate

Formula: H4P2O7 (177.9432294)

CAS ID: 2466-09-3

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Magnesium cation

Formula: Mg (23.98505)

CAS ID: 22537-22-0

N-Acetyl-beta-D-glucosamine

Formula: C8H15NO6 (221.089933)

CAS ID: 14131-68-1

N-Ethylmaleimide

Formula: C6H7NO2 (125.0476762)

CAS ID: 128-53-0

Potassium cation

Formula: K (38.963708)

CAS ID: 24203-36-9

Zinc cation

Formula: Zn (63.929145)

CAS ID: 23713-49-7

iodoacetamide

Formula: C2H4INO (184.9337644)

CAS ID: 144-48-9

acetate

Formula: C2H3O2 (59.0133038)

CAS ID: 71-50-1

NADPH(4-)

Formula: C21H26N7O17P3 (741.0598016)

CAS ID: 53-57-6

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:

UDP-N-acetyl-alpha-D-muramate(3-)

Formula: C20H28N3O19P2 (676.0792218)

CAS ID:

UDP-N-acetyl-alpha-D-glucosamine 3-phosphate(4-)

Formula: C17H24N3O20P3 (683.0166014)

CAS ID:

ADP(3-)

Formula: C10H12N5O10P2 (424.0059412)

CAS ID:

NADP(3-)

Formula: C21H25N7O17P3 (740.051977)

CAS ID: 53-59-8

p-hydroxymercuribenzoic acid

Formula: C7H6HgO3 (340.00232459999995)

CAS ID: 1126-48-3

bromoacetate

Formula: C2H2BrO2 (136.9238152)

CAS ID: 68-10-0

Dithionitrobenzoic acid

Formula: C14H6N2O8S2-2 (393.9565596)

CAS ID:



Enzyme

EC Number name full name note
3.4.-.-
1.3.1.98 UDP-N-acetylmuramate dehydrogenase UDP-N-acetyl-alpha-D-muramate:NADP+ oxidoreductase
2.3.1.157 glucosamine-1-phosphate N-acetyltransferase acetyl-CoA:alpha-D-glucosamine-1-phosphate N-acetyltransferase
2.5.1.7 UDP-N-acetylglucosamine 1-carboxyvinyltransferase phosphoenolpyruvate:UDP-N-acetyl-D-glucosamine 1-carboxyvinyltransferase
2.7.1.170 anhydro-N-acetylmuramic acid kinase ATP:1,6-anhydro-N-acetyl-beta-muramate 6-phosphotransferase
2.7.7.23 UDP-N-acetylglucosamine diphosphorylase UTP:N-acetyl-alpha-D-glucosamine-1-phosphate uridylyltransferase
3.2.1.52 beta-N-acetylhexosaminidase beta-N-acetyl-D-hexosaminide N-acetylhexosaminohydrolase
3.4.17.13 Muramoyltetrapeptide carboxypeptidase
3.5.1.25 N-acetylglucosamine-6-phosphate deacetylase N-acetyl-D-glucosamine-6-phosphate amidohydrolase
3.5.1.28 N-acetylmuramoyl-L-alanine amidase peptidoglycan amidohydrolase
4.2.1.126 N-acetylmuramic acid 6-phosphate etherase (R)-lactate hydro-lyase (adding N-acetyl-D-glucosamine 6-phosphate; N-acetylmuramate 6-phosphate-forming)
5.4.2.10 phosphoglucosamine mutase alpha-D-glucosamine 1,6-phosphomutase
6.3.2.45 UDP-N-acetylmuramate-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate ligase UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate ligase


Proteins

Protein ID name full name
P08373 murB UDP-N-acetylenolpyruvoylglucosamine reductase
P0A749 murA UDP-N-acetylglucosamine 1-carboxyvinyltransferase
P0ACC7 glmU Bifunctional protein GlmU
P0AF18 nagA N-acetylglucosamine-6-phosphate deacetylase
P0AFV4 mepS Murein DD-endopeptidase MepS/Murein LD-carboxypeptidase
P13016 ampD 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD
P31120 glmM Phosphoglucosamine mutase
P37773 mpl UDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptandioate ligase
P75820 amiD N-acetylmuramoyl-L-alanine amidase AmiD
P75949 nagZ Beta-hexosaminidase
P76008 ldcA Murein tetrapeptide carboxypeptidase
P76535 murQ N-acetylmuramic acid 6-phosphate etherase
P77570 anmK Anhydro-N-acetylmuramic acid kinase