superpathway of ergosterol biosynthesis

Sun LM, Lv BB, Cheng AX, Wu XZ, Lou HX. The Effect of Plagiochin E Alone and in Combination with Fluconazole on the Ergosterol Biosynthesis of Candida albicans. Biological & Pharmaceutical Bulletin. 2009;32(1):36–40. doi: 10.1248/bpb.32.36.

Metabolites

(R)-5-Diphosphomevalonate

Formula: C6H14O10P2 (308.0062204)

CAS ID: 103025-21-4

(R)-5-Phosphomevalonate

Formula: C6H13O7P (228.0398878)

CAS ID: 73566-35-5

(R)-Mevalonate

Formula: C6H12O4 (148.0735552)

CAS ID: 17817-88-8

ADP

Formula: C10H15N5O10P2 (427.02941500000003)

CAS ID: 58-64-0

ATP

Formula: C10H16N5O13P3 (506.9957476)

CAS ID: 56-65-5

CO2

Formula: CO2 (43.98983)

CAS ID: 124-38-9

Diphosphate

Formula: H4P2O7 (177.9432294)

CAS ID: 2466-09-3

DMPP

Formula: C12H19N2. I (318.0592924)

CAS ID: 54-77-3

Fecosterol

Formula: C28H46O (398.3548466)

CAS ID: 516-86-9

Formate

Formula: CH2O2 (46.0054792)

CAS ID: 64-18-6

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Isopentenyl diphosphate

Formula: C5H12O7P2 (246.0058262)

CAS ID: 358-71-4

Lanosterol

Formula: C30H50O (426.386145)

CAS ID: 79-63-0

NADP+

Formula: C21H29N7O17P3 (744.0832754)

CAS ID: 53-59-8

NADPH

Formula: C21H30N7O17P3 (745.0911)

CAS ID: 2646-71-1

Orthophosphate

Formula: H3PO4 (97.9768968)

CAS ID: 7664-38-2

Oxygen

Formula: O2 (31.98983)

CAS ID: 7782-44-7

S-Adenosyl-L-homocysteine

Formula: C14H20N6O5S (384.12158300000004)

CAS ID: 979-92-0

trans,trans-Farnesyl diphosphate

Formula: C15H28O7P2 (382.1310198)

CAS ID: 372-97-4

S-Adenosylmethionine

Formula: C15H23N6O5S (399.1450568)

CAS ID: 485-80-3

Squalene, analytical standard

Formula: C30H50 (410.39123)

CAS ID:



Enzyme

EC Number name full name note


Proteins

Protein ID name full name