Purine Nucleotides De Novo Biosynthesis
Metabolites
1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
Formula: C9H14N3O9P (339.04676440000003)
CAS ID: 6001-14-5
1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
Formula: C13H19N4O12P (454.07370640000005)
CAS ID: 3031-95-6
1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
Formula: C9H15N4O8P (338.062748)
CAS ID: 3031-94-5
1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
Formula: C10H15N4O9P (366.057663)
CAS ID: 13018-54-7
Enzyme
| EC Number | name | full name | note |
|---|---|---|---|
| 2.1.2.3 | phosphoribosylaminoimidazolecarboxamide formyltransferase | 10-formyltetrahydrofolate:5'-phosphoribosyl-5-amino-4-imidazole-carboxamide N-formyltransferase | |
| 2.7.4.3 | adenylate kinase | ATP:AMP phosphotransferase | |
| 2.7.4.6 | nucleoside-diphosphate kinase | ATP:nucleoside-diphosphate phosphotransferase | |
| 3.5.4.10 | IMP cyclohydrolase | IMP 1,2-hydrolase (decyclizing) | |
| 6.3.1.21 | phosphoribosylglycinamide formyltransferase 2 | formate:N1-(5-phospho-beta-D-ribosyl)glycinamide ligase (ADP-forming) | |
| 6.3.2.6 | phosphoribosylaminoimidazolesuccinocarboxamide synthase | 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate:L-aspartate ligase (ADP-forming) | |
| 6.3.3.1 | phosphoribosylformylglycinamidine cyclo-ligase | 2-(Formamido)-N1-(5-phosphoribosyl)acetamidine cyclo-ligase (ADP-forming) | |
| 6.3.4.4 | adenylosuccinate synthase | IMP:L-aspartate ligase (GDP-forming) | |
| 6.3.5.2 | GMP synthase (glutamine-hydrolysing) | xanthosine-5'-phosphate:L-glutamine amido-ligase (AMP-forming) | |
| 7.1.2.2 | H+-transporting two-sector ATPase | ATP phosphohydrolase (H+-transporting) |
Proteins
| Protein ID | name | full name |
|---|---|---|
| A6V0V6 | ndk | Nucleoside diphosphate kinase |
| A6V1A1 | adk | Adenylate kinase |
| A6V9K1 | purC | Phosphoribosylaminoimidazole-succinocarboxamide synthase |
| A6VF32 | atpD | ATP synthase subunit beta |
| A6VF34 | atpA | ATP synthase subunit alpha |
| B7UXJ9 | guaA | GMP synthase [glutamine-hydrolyzing] |
| B7UXY9 | purM | Phosphoribosylformylglycinamidine cyclo-ligase |
| B7UYK0 | purT | Formate-dependent phosphoribosylglycinamide formyltransferase |
| B7V201 | purA | Adenylosuccinate synthetase |
| Q02FG6 | purH | Bifunctional purine biosynthesis protein PurH |