N-Acetylneuraminate, N-Acetylmannosamine, and N-Acetylglucosamine Degradation

Metabolites

Acetate

Formula: C2H4O2 (60.0211284)

CAS ID: 64-19-7

ADP

Formula: C10H15N5O10P2 (427.02941500000003)

CAS ID: 58-64-0

ATP

Formula: C10H16N5O13P3 (506.9957476)

CAS ID: 56-65-5

D-Glucosamine 6-phosphate

Formula: C6H14NO8P (259.04570140000004)

CAS ID: 3616-42-0

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

N-Acetyl-beta-neuraminate

Formula: C11H19NO9 (309.10597640000003)

CAS ID: 19342-33-7

N-Acetyl-D-glucosamine 6-phosphate

Formula: C8H16NO9P (301.0562656)

CAS ID: 18191-20-3

N-Acetyl-D-mannosamine

Formula: C8H15NO6 (221.089933)

CAS ID: 3615-17-6

N-Acetyl-D-mannosamine 6-phosphate

Formula: C8H16NO9P (301.0562656)

CAS ID: 873185-52-5

NH4+

Formula: NH4 (18.0343724)

CAS ID: 14798-03-9

Pyruvate

Formula: C3H4O3 (88.0160434)

CAS ID: 127-17-3



Enzyme

EC Number name full name note
2.7.1.60 N-acylmannosamine kinase ATP:N-acyl-D-mannosamine 6-phosphotransferase
3.5.1.25 N-acetylglucosamine-6-phosphate deacetylase N-acetyl-D-glucosamine-6-phosphate amidohydrolase
3.5.99.6 glucosamine-6-phosphate deaminase 2-amino-2-deoxy-D-glucose-6-phosphate aminohydrolase (ketol isomerizing)
4.1.3.3 N-acetylneuraminate lyase aceneuramate pyruvate-lyase (N-acetyl-D-mannosamine-forming)
5.1.3.9 N-acylglucosamine-6-phosphate 2-epimerase N-acyl-D-glucosamine-6-phosphate 2-epimerase


Proteins

Protein ID name full name
P0A6L4 nanA N-acetylneuraminate lyase
P0A759 nagB Glucosamine-6-phosphate deaminase
P0A761 nanE Putative N-acetylmannosamine-6-phosphate 2-epimerase
P0AF18 nagA N-acetylglucosamine-6-phosphate deacetylase
P45425 nanK N-acetylmannosamine kinase