Glutathione Metabolism III

Metabolites

1-Aminopropan-2-ol

Formula: C3H9NO (75.0684104)

CAS ID: 78-96-6

3,4-Dihydro-3-hydroxy-4-S-glutathionyl bromobenzene

Formula: C16H22BrN3O7S (479.03617620000006)

CAS ID:

ADP

Formula: C10H15N5O10P2 (427.02941500000003)

CAS ID: 58-64-0

ATP

Formula: C10H16N5O13P3 (506.9957476)

CAS ID: 56-65-5

Benzo[a]pyrene-4,5-oxide

Formula: C20H12O (268.0888102)

CAS ID: 37574-47-3

Bromobenzene-3,4-oxide

Formula: C6H5BrO (171.952374)

CAS ID: 51981-75-0

gamma-L-Glutamyl-L-cysteine

Formula: C8H14N2O5S (250.0623394)

CAS ID: 636-58-8

Glutathione

Formula: C10H17N3O6S (307.08380220000004)

CAS ID: 70-18-8

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Hydrochloric acid

Formula: HCl (35.9766776)

CAS ID: 7647-01-0

L-Cysteine

Formula: C3H7NO2S (121.0197482)

CAS ID: 52-90-4

L-Glutamate

Formula: C5H9NO4 (147.0531554)

CAS ID: 56-86-0

NADP+

Formula: C21H29N7O17P3 (744.0832754)

CAS ID: 53-59-8

Sodium cation

Formula: Na (22.98977)

CAS ID: 17341-25-2

phosphate(3-)

Formula: O4P (94.953423)

CAS ID: 14265-44-2



Enzyme

EC Number name full name note
1.11.1.-
1.8.1.7 glutathione-disulfide reductase glutathione:NADP+ oxidoreductase
2.5.1.18 glutathione transferase RX:glutathione R-transferase
6.3.2.2 glutamate-cysteine ligase L-glutamate:L-cysteine gamma-ligase (ADP-forming)
6.3.2.3 glutathione synthase gamma-L-glutamyl-L-cysteine:glycine ligase (ADP-forming)
7.4.2.1 ABC-type polar-amino-acid transporter ATP phosphohydrolase (ABC-type, polar-amino-acid-importing)


Proteins

Protein ID name full name
P04425 gshB Glutathione synthetase
P06715 gor Glutathione reductase
P0A6W9 gshA Glutamate--cysteine ligase
P0A9D2 gstA Glutathione S-transferase GstA
P0AAG3 gltL Glutamate/aspartate import ATP-binding protein GltL
P77526 yfcG Disulfide-bond oxidoreductase YfcG