L-valine biosynthesis

Metabolites

CO2

Formula: CO2 (43.98983)

CAS ID: 124-38-9

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

2-oxoglutarate(2-)

Formula: C5H4O5 (144.00587339999998)

CAS ID: 64-15-3

3-methyl-2-oxobutanoate

Formula: C5H7O3 (115.0395172)

CAS ID:

pyruvate

Formula: C3H3O3 (87.00821880000001)

CAS ID: 57-60-3

NADPH(4-)

Formula: C21H26N7O17P3 (741.0598016)

CAS ID: 53-57-6

NADP(3-)

Formula: C21H25N7O17P3 (740.051977)

CAS ID: 53-59-8



Enzyme

EC Number name full name note
1.1.1.86 ketol-acid reductoisomerase (NADP+) (R)-2,3-dihydroxy-3-methylbutanoate:NADP+ oxidoreductase (isomerizing)
2.2.1.6 acetolactate synthase pyruvate:pyruvate acetaldehydetransferase (decarboxylating)
2.6.1.42 branched-chain-amino-acid transaminase branched-chain-amino-acid:2-oxoglutarate aminotransferase
4.2.1.9 dihydroxy-acid dehydratase 2,3-dihydroxy-3-methylbutanoate hydro-lyase (3-methyl-2-oxobutanoate-forming)


Proteins

Protein ID name full name
O06335 ilvB2 Probable acetolactate synthase (large subunit) IlvB2 (AHAS) (acetohydroxy-acid synthase large subunit) (ALS)
O53554 ilvX Probable acetohydroxyacid synthase IlvX (acetolactate synthase)
P9WG39 ilvG Acetolactate synthase large subunit IlvG
P9WG41 ilvB1 Acetolactate synthase large subunit IlvB1
P9WKJ3 ilvH Putative acetolactate synthase small subunit
P9WKJ5 ilvD Dihydroxy-acid dehydratase
P9WKJ7 ilvC Ketol-acid reductoisomerase (NADP(+))
P9WQ75 ilvE Branched-chain-amino-acid aminotransferase