NAD de novo biosynthesis I (from aspartate)

Metabolites

CO2

Formula: CO2 (43.98983)

CAS ID: 124-38-9

Diphosphate

Formula: H4P2O7 (177.9432294)

CAS ID: 2466-09-3

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Hydrogen peroxide

Formula: H2O2 (34.0054792)

CAS ID: 7722-84-1

Magnesium cation

Formula: Mg (23.98505)

CAS ID: 22537-22-0

Oxygen

Formula: O2 (31.98983)

CAS ID: 7782-44-7

Pyrazinamide

Formula: C5H5N3O (123.04326000000002)

CAS ID: 98-96-4

iminoaspartate

Formula: C4H3NO4 (129.0062078)

CAS ID:

L-aspartate(1-)

Formula: C4H6NO4 (132.0296816)

CAS ID:

pyrazine-2-carboxylate

Formula: C5H3N2O2 (123.0194518)

CAS ID:

adenosine 5'-monophosphate(2-)

Formula: C10H12N5O7P (345.0474332)

CAS ID:

deamido-NAD(2-)

Formula: C21H24N6O15P2 (662.0774854)

CAS ID:

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:

NAD(1-)

Formula: C21H26N7O14P2 (662.1012936000001)

CAS ID: 53-84-9



Enzyme

EC Number name full name note
1.4.3.16 L-aspartate oxidase L-aspartate:oxygen oxidoreductase
2.4.2.19 nicotinate-nucleotide diphosphorylase (carboxylating) nicotinate-D-ribonucleotide:diphosphate phospho-alpha-D-ribosyltransferase (carboxylating)
2.5.1.72 quinolinate synthase glycerone phosphate:iminosuccinate alkyltransferase (cyclizing)
2.7.7.18 nicotinate-nucleotide adenylyltransferase ATP:nicotinate-ribonucleotide adenylyltransferase
6.3.5.1 NAD+ synthase (glutamine-hydrolysing) deamido-NAD+:L-glutamine amido-ligase (AMP-forming)


Proteins

Protein ID name full name
P9WJJ3 nadE Glutamine-dependent NAD(+) synthetase
P9WJJ5 nadD Probable nicotinate-nucleotide adenylyltransferase
P9WJJ7 nadC Nicotinate-nucleotide pyrophosphorylase [carboxylating]
P9WJJ9 nadB L-aspartate oxidase
P9WJK1 nadA Quinolinate synthase