Tyrosine metabolism and related disorders
Hendrikse NM, Holmberg Larsson A, Svensson Gelius S, Kuprin S, Nordling E, Syrén P. Exploring the therapeutic potential of modern and ancestral phenylalanine/tyrosine ammonia-lyases as supplementary treatment of hereditary tyrosinemia. Scientific Reports. 2020 Jan 28;10(1):1315. doi: 10.1038/s41598-020-57913-y.
Metabolites
Enzyme
| EC Number | name | full name | note |
|---|---|---|---|
| 1.13.11.27 | 4-hydroxyphenylpyruvate dioxygenase | 4-hydroxyphenylpyruvate:oxygen oxidoreductase (hydroxylating, decarboxylating) | |
| 1.13.11.5 | homogentisate 1,2-dioxygenase | homogentisate:oxygen 1,2-oxidoreductase (decyclizing) | |
| 2.6.1.5 | tyrosine transaminase | L-tyrosine:2-oxoglutarate aminotransferase | |
| 3.7.1.2 | fumarylacetoacetase | 4-fumarylacetoacetate fumarylhydrolase |
Proteins
| Protein ID | name | full name |
|---|