PDGF pathway

Heldin C, Hammacher A, Nistér M, Westermark B. Structural and functional aspects of platelet-derived growth factor. British Journal of Cancer. 1988 Dec;57(6):591–3. doi: 10.1038/bjc.1988.134.

Metabolites

3',5'-Cyclic AMP

Formula: C10H12N5O6P (329.0525182)

CAS ID: 60-92-4

Arachidonate

Formula: C20H32O2 (304.24021719999996)

CAS ID: 506-32-1

Calcium cation

Formula: Ca (39.962591)

CAS ID: 14127-61-8

D-myo-Inositol 1,4,5-trisphosphate

Formula: C6H15O15P3 (419.96238300000005)

CAS ID: 85166-31-0

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

Sodium cation

Formula: Na (22.98977)

CAS ID: 17341-25-2

PIP2[4',5'](17:0/20:4(5Z,8Z,11Z,14Z))

Formula: C46H83O19P3 (1032.4741158000002)

CAS ID:



Enzyme

EC Number name full name note
2.7.10.2 non-specific protein-tyrosine kinase ATP:[protein]-L-tyrosine O-phosphotransferase (non-specific)
2.7.11.1 non-specific serine/threonine protein kinase ATP:protein phosphotransferase (non-specific)
2.7.11.10 IkappaB kinase ATP:[IkappaB protein] phosphotransferase
3.6.5.2 small monomeric GTPase GTP phosphohydrolase (cell-regulating)
7.1.1.9 cytochrome-c oxidase ferrocytochrome-c:oxygen oxidoreductase


Proteins

Protein ID name full name