EPHB-mediated forward signaling

Shi Y, Pontrello CG, DeFea KA, Reichardt LF, Ethell IM. Focal Adhesion Kinase Acts Downstream of EphB Receptors to Maintain Mature Dendritic Spines by Regulating Cofilin Activity. Journal of Neuroscience. 2009 Jun 24;29(25):8129–42. doi: 10.1523/jneurosci.4681-08.2009.; Moeller ML, Shi Y, Reichardt LF, Ethell IM. EphB Receptors Regulate Dendritic Spine Morphogenesis through the Recruitment/Phosphorylation of Focal Adhesion Kinase and RhoA Activation. Journal of Biological Chemistry. 2006 Jan;281(3):1587–98. doi: 10.1074/jbc.m511756200.; Murai KK, Pasquale EB. 'Eph'ective signaling: forward, reverse and crosstalk. J Cell Sci. 2003 Jul 15;116(Pt 14):2823–32. doi: 10.1242/jcs.00625. PMID: 12808016.

Metabolites

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:

GTP(4-)

Formula: C10H12N5O14P3 (518.9593642)

CAS ID: 86527-72-2

ADP(3-)

Formula: C10H12N5O10P2 (424.0059412)

CAS ID:



Enzyme

EC Number name full name note
3.6.4.-
3.6.5.2 small monomeric GTPase GTP phosphohydrolase (cell-regulating)


Proteins

Protein ID name full name