Signaling by NTRK1 (TRKA)

Huang EJ, Reichardt LF. Trk receptors: roles in neuronal signal transduction. Annu Rev Biochem. 2003;72():609–42. doi: 10.1146/annurev.biochem.72.121801.161629. PMID: 12676795.; Sofroniew MV, Howe CL, Mobley WC. Nerve growth factor signaling, neuroprotection, and neural repair. Annu Rev Neurosci. 2001;24():1217–81. doi: 10.1146/annurev.neuro.24.1.1217. PMID: 11520933.; Kaplan DR, Miller FD. Neurotrophin signal transduction in the nervous system. Curr Opin Neurobiol. 2000 Jun;10(3):381–91. doi: 10.1016/s0959-4388(00)00092-1. PMID: 10851172.; Friedman WJ, Greene LA. Neurotrophin signaling via Trks and p75. Exp Cell Res. 1999 Nov 25;253(1):131–42. doi: 10.1006/excr.1999.4705. PMID: 10579918.

Metabolites

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:

ADP(3-)

Formula: C10H12N5O10P2 (424.0059412)

CAS ID:



Enzyme

EC Number name full name note
2.7.11.1 non-specific serine/threonine protein kinase ATP:protein phosphotransferase (non-specific)
2.7.11.24 mitogen-activated protein kinase ATP:protein phosphotransferase (MAPKK-activated)


Proteins

Protein ID name full name
P32485 HOG1 Mitogen-activated protein kinase HOG1
P38070 YPK3 Serine/threonine-protein kinase YPK3
Q00772 SLT2 Mitogen-activated protein kinase SLT2/MPK1