Toll-like Receptor Cascades

Kawai T, Akira S. Pathogen recognition with Toll-like receptors. Curr Opin Immunol. 2005 Aug;17(4):338–44. doi: 10.1016/j.coi.2005.02.007. PMID: 15950447.; Heine H, Ulmer AJ. Recognition of bacterial products by toll-like receptors. Chem Immunol Allergy. 2005;86():99–119. doi: 10.1159/000086654. PMID: 15976490.; Takeda K, Akira S. Toll-like receptors in innate immunity. Int Immunol. 2005 Jan;17(1):1–14. doi: 10.1093/intimm/dxh186. PMID: 15585605.; Takeda K, Akira S. TLR signaling pathways. Semin Immunol. 2004 Feb;16(1):3–9. doi: 10.1016/j.smim.2003.10.003. PMID: 14751757.; Akira S. Toll-like Receptor Signaling. Journal of Biological Chemistry. 2003 Oct;278(40):38105–8. doi: 10.1074/jbc.r300028200.

Metabolites

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:

ADP(3-)

Formula: C10H12N5O10P2 (424.0059412)

CAS ID:



Enzyme

EC Number name full name note
2.7.11.1 non-specific serine/threonine protein kinase ATP:protein phosphotransferase (non-specific)
2.7.11.24 mitogen-activated protein kinase ATP:protein phosphotransferase (MAPKK-activated)


Proteins

Protein ID name full name
P32485 HOG1 Mitogen-activated protein kinase HOG1
P38070 YPK3 Serine/threonine-protein kinase YPK3
Q00772 SLT2 Mitogen-activated protein kinase SLT2/MPK1