BDNF activates NTRK2 (TRKB) signaling
Ohira K, Shimizu K, Hayashi M. TrkB dimerization during development of the prefrontal cortex of the macaque. J Neurosci Res. 2001 Sep 01;65(5):463–9. doi: 10.1002/jnr.1175. PMID: 11536331.; McCarty JH, Feinstein SC. The TrkB receptor tyrosine kinase regulates cellular proliferation via signal transduction pathways involving SHC, PLCgamma, and CBL. J Recept Signal Transduct Res. 1999 Nov;19(6):953–74. doi: 10.3109/10799899909038434. PMID: 10533983.; Minichiello L, Casagranda F, Tatche RS, Stucky CL, Postigo A, Lewin GR, Davies AM, Klein R. Point mutation in trkB causes loss of NT4-dependent neurons without major effects on diverse BDNF responses. Neuron. 1998 Aug;21(2):335–45. doi: 10.1016/s0896-6273(00)80543-7. PMID: 9728915.; Guiton M, Gunn-Moore FJ, Stitt TN, Yancopoulos GD, Tavaré JM. Identification of in vivo brain-derived neurotrophic factor-stimulated autophosphorylation sites on the TrkB receptor tyrosine kinase by site-directed mutagenesis. Journal of Biological Chemistry. 1994 Dec;269(48):30370–7. doi: 10.1016/s0021-9258(18)43823-9.; Klein R, Nanduri V, Jing SA, Lamballe F, Tapley P, Bryant S, Cordon-Cardo C, Jones KR, Reichardt LF, Barbacid M. The trkB tyrosine protein kinase is a receptor for brain-derived neurotrophic factor and neurotrophin-3. Cell. 1991 Jul 26;66(2):395–403. PMID: 1649702; PMCID: PMC2710095.; Soppet D, Escandon E, Maragos J, Middlemas DS, Reid SW, Blair J, Burton LE, Stanton BR, Kaplan DR, Hunter T, Nikolics K, Parada LF. The neurotrophic factors brain-derived neurotrophic factor and neurotrophin-3 are ligands for the trkB tyrosine kinase receptor. Cell. 1991 May 31;65(5):895–903. doi: 10.1016/0092-8674(91)90396-g. PMID: 1645620.