Recognition and association of DNA glycosylase with site containing an affected purine

Parikh SS, Mol CD, Slupphaug G, Bharati S, Krokan HE, Tainer JA. Base excision repair initiation revealed by crystal structures and binding kinetics of human uracil-DNA glycosylase with DNA. EMBO J. 1998 Sep 01;17(17):5214–26. PMID: 9724657; PMCID: PMC1170849.; Slupphaug G, Mol CD, Kavli B, Arvai AS, Krokan HE, Tainer JA. A nucleotide-flipping mechanism from the structure of human uracil-DNA glycosylase bound to DNA. Nature. 1996 Nov 07;384(6604):87–92. doi: 10.1038/384087a0. PMID: 8900285.

Metabolites



Enzyme

EC Number name full name note
3.2.2.-
3.2.2.21 DNA-3-methyladenine glycosylase II alkylated-DNA glycohydrolase (releasing methyladenine and methylguanine)
4.2.99.18 DNA-(apurinic or apyrimidinic site) lyase DNA-(apurinic or apyrimidinic site) 5'-phosphomonoester-lyase


Proteins

Protein ID name full name