Phospholipase C-mediated cascade: FGFR1

Eswarakumar VP, Lax I, Schlessinger J. Cellular signaling by fibroblast growth factor receptors. Cytokine Growth Factor Rev. 2005 Apr;16(2):139–49. doi: 10.1016/j.cytogfr.2005.01.001. PMID: 15863030.; Carpenter G, Ji Qs. Phospholipase C-gamma as a signal-transducing element. Exp Cell Res. 1999 Nov 25;253(1):15–24. doi: 10.1006/excr.1999.4671. PMID: 10579907.; Mohammadi M, Honegger AM, Rotin D, Fischer R, Bellot F, Li W, Dionne CA, Jaye M, Rubinstein M, Schlessinger J. A Tyrosine-Phosphorylated Carboxy-Terminal Peptide of the Fibroblast Growth Factor Receptor (Flg) Is a Binding Site for the SH2 Domain of Phospholipase C-?1. Molecular and Cellular Biology. 1991 Oct 01;11(10):5068–78. doi: 10.1128/mcb.11.10.5068-5078.1991.

Metabolites

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:

ADP(3-)

Formula: C10H12N5O10P2 (424.0059412)

CAS ID:



Enzyme

EC Number name full name note
2.7.10.1 receptor protein-tyrosine kinase ATP:[protein]-L-tyrosine O-phosphotransferase (receptor-type)


Proteins

Protein ID name full name