Beta-catenin independent WNT signaling

Saito-Diaz K, Chen TW, Wang X, Thorne CA, Wallace HA, Page-McCaw A, Lee E. The way Wnt works: Components and mechanism. Growth Factors. 2012 Dec 21;31(1):1–31. doi: 10.3109/08977194.2012.752737.; van Amerongen R. Alternative Wnt Pathways and Receptors. Cold Spring Harbor Perspectives in Biology. 2012 Aug 30;4(10):a007914. doi: 10.1101/cshperspect.a007914.; Gao B. Wnt regulation of planar cell polarity (PCP). Curr Top Dev Biol. 2012;101():263–95. doi: 10.1016/b978-0-12-394592-1.00008-9. PMID: 23140633.; De A. Wnt/Ca2+ signaling pathway: a brief overview. Acta Biochim Biophys Sin (Shanghai). 2011 Oct;43(10):745–56. doi: 10.1093/abbs/gmr079. PMID: 21903638.; Du SJ, Purcell SM, Christian JL, McGrew LL, Moon RT. Identification of Distinct Classes and Functional Domains of Wnts through Expression of Wild-Type and Chimeric Proteins in Xenopus Embryos. Molecular and Cellular Biology. 1995 May 01;15(5):2625–34. doi: 10.1128/mcb.15.5.2625.; Wong GT, Gavin BJ, Mcmahon AP. Differential Transformation of Mammary Epithelial Cells by Wnt Genes. Molecular and Cellular Biology. 1994 Sep 01;14(9):6278–86. doi: 10.1128/mcb.14.9.6278-6286.1994.

Metabolites

Calcium cation

Formula: Ca (39.962591)

CAS ID: 14127-61-8

Fe3+

Formula: Fe (55.934939)

CAS ID: 7439-89-6

Magnesium cation

Formula: Mg (23.98505)

CAS ID: 22537-22-0

Zinc cation

Formula: Zn (63.929145)

CAS ID: 23713-49-7

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:

GTP(4-)

Formula: C10H12N5O14P3 (518.9593642)

CAS ID: 86527-72-2

ADP(3-)

Formula: C10H12N5O10P2 (424.0059412)

CAS ID:



Enzyme

EC Number name full name note
2.7.11.13 protein kinase C ATP:protein phosphotransferase (diacylglycerol-dependent)
2.7.11.17 Ca2+/calmodulin-dependent protein kinase ATP:protein phosphotransferase (Ca2+/calmodulin-dependent)
2.7.11.24 mitogen-activated protein kinase ATP:protein phosphotransferase (MAPKK-activated)
3.1.3.16 protein-serine/threonine phosphatase protein-serine/threonine-phosphate phosphohydrolase
3.6.5.2 small monomeric GTPase GTP phosphohydrolase (cell-regulating)


Proteins

Protein ID name full name