Class I MHC mediated antigen processing & presentation
Wearsch PA, Cresswell P. The quality control of MHC class I peptide loading. Current Opinion in Cell Biology. 2008 Dec;20(6):624–31. doi: 10.1016/j.ceb.2008.09.005.; Vyas JM, Van der Veen AG, Ploegh HL. The known unknowns of antigen processing and presentation. Nat Rev Immunol. 2008 Aug;8(8):607–18. PMID: 18641646; PMCID: PMC2735460.; Purcell AW, Elliott T. Molecular machinations of the MHC-I peptide loading complex. Curr Opin Immunol. 2008 Feb;20(1):75–81. doi: 10.1016/j.coi.2007.12.005. PMID: 18243674.; Elliott T, Neefjes J. The complex route to MHC class I-peptide complexes. Cell. 2006 Oct 20;127(2):249–51. doi: 10.1016/j.cell.2006.10.001. PMID: 17055423.; Loureiro J, Ploegh HL. Antigen presentation and the ubiquitin-proteasome system in host-pathogen interactions. Adv Immunol. 2006;92():225–305. PMID: 17145306; PMCID: PMC7112114.; Antoniou AN, Powis SJ, Elliott T. Assembly and export of MHC class I peptide ligands. Curr Opin Immunol. 2003 Feb;15(1):75–81. doi: 10.1016/s0952-7915(02)00010-9. PMID: 12495737.; York IA, Rock KL. Antigen processing and presentation by the class I major histocompatibility complex. Annu Rev Immunol. 1996;14():369–96. doi: 10.1146/annurev.immunol.14.1.369. PMID: 8717519.
Metabolites
Enzyme
| EC Number | name | full name | note |
|---|---|---|---|
| 3.6.5.2 | small monomeric GTPase | GTP phosphohydrolase (cell-regulating) |
Proteins
| Protein ID | name | full name |
|---|