Glycosphingolipid metabolism
Sandhoff R, Sandhoff K. Emerging concepts of ganglioside metabolism. FEBS Lett. 2018 Dec;592(23):3835–64. doi: 10.1002/1873-3468.13114. PMID: 29802621.; Sandhoff R, Schulze H, Sandhoff K. Ganglioside Metabolism in Health and Disease. Prog Mol Biol Transl Sci. 2018;156():1–62. doi: 10.1016/bs.pmbts.2018.01.002. PMID: 29747811.; Gault CR, Obeid LM, Hannun YA. An overview of sphingolipid metabolism: from synthesis to breakdown. Adv Exp Med Biol. 2010;688():1–23. PMID: 20919643; PMCID: PMC3069696.
Metabolites
Enzyme
| EC Number | name | full name | note |
|---|---|---|---|
| 3.5.1.- | |||
| 1.8.3.7 | formylglycine-generating enzyme | [sulfatase]-L-cysteine:oxygen oxidoreductase (3-oxo-L-alanine-forming) | |
| 3.1.4.12 | sphingomyelin phosphodiesterase | sphingomyelin cholinephosphohydrolase | |
| 3.1.4.3 | phospholipase C | phosphatidylcholine cholinephosphohydrolase | |
| 3.1.6.8 | cerebroside-sulfatase | cerebroside-3-sulfate 3-sulfohydrolase | |
| 3.5.1.23 | ceramidase | N-acylsphingosine amidohydrolase |
Proteins
| Protein ID | name | full name |
|---|