Pentose phosphate pathway

Wamelink MM, Struys EA, Jakobs C. The biochemistry, metabolism and inherited defects of the pentose phosphate pathway: a review. J Inherit Metab Dis. 2008 Dec;31(6):703–17. doi: 10.1007/s10545-008-1015-6. PMID: 18987987.; Casazza JP, Veech RL. The content of pentose-cycle intermediates in liver in starved, fed ad libitum and meal-fed rats. Biochem J. 1986 Jun 15;236(3):635–41. PMID: 3790084; PMCID: PMC1146893.; Luzzatto L, Afolayan A. Enzymic properties of different types of human erythrocyte glucose-6-phosphate dehydrogenase, with characterization of two new genetic variants. J Clin Invest. 1968 Aug;47(8):1833–42. PMID: 5666113; PMCID: PMC297343.

Metabolites

Acetaldehyde

Formula: C2H4O (44.0262134)

CAS ID: 75-07-0

CO2

Formula: CO2 (43.98983)

CAS ID: 124-38-9

D-Ribose

Formula: C5H10O5 (150.052821)

CAS ID: 50-69-1

Fe2+

Formula: Fe (55.934939)

CAS ID: 15438-31-0

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Magnesium cation

Formula: Mg (23.98505)

CAS ID: 22537-22-0

adenosine 5'-monophosphate(2-)

Formula: C10H12N5O7P (345.0474332)

CAS ID:

2-deoxy-alpha-D-ribose 1-phosphate(2-)

Formula: C5H9O7P (212.00858939999998)

CAS ID:

NADPH(4-)

Formula: C21H26N7O17P3 (741.0598016)

CAS ID: 53-57-6

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:

thiamine(1+) diphosphate(3-)

Formula: C12H16N4O7P2S (422.0214926)

CAS ID:

ADP(3-)

Formula: C10H12N5O10P2 (424.0059412)

CAS ID:

6-O-phosphonato-D-glucono-1,5-lactone(2-)

Formula: C6H9O9P (255.99841940000002)

CAS ID:

NADP(3-)

Formula: C21H25N7O17P3 (740.051977)

CAS ID: 53-59-8



Enzyme

EC Number name full name note
2.7.6.1 ribose-phosphate diphosphokinase ATP:D-ribose-5-phosphate diphosphotransferase
4.1.2.4 deoxyribose-phosphate aldolase 2-deoxy-D-ribose-5-phosphate acetaldehyde-lyase (D-glyceraldehyde-3-phosphate-forming)


Proteins

Protein ID name full name