activated TAK1 mediates p38 MAPK activation
Li J, Nie L, Zhao Y, Zhang Y, Wang X, Wang S, Liu Y, Zhao H, Cheng L. IL-17 mediates inflammatory reactions via p38/c-Fos and JNK/c-Jun activation in an AP-1-dependent manner in human nucleus pulposus cells. Journal of Translational Medicine. 2016 Mar 17;14(1):77. doi: 10.1186/s12967-016-0833-9.; Thiefes A, Wolter S, Mushinski JF, Hoffmann E, Dittrich-Breiholz O, Graue N, Dörrie A, Schneider H, Wirth D, Luckow B, Resch K, Kracht M. Simultaneous blockade of NFkappaB, JNK, and p38 MAPK by a kinase-inactive mutant of the protein kinase TAK1 sensitizes cells to apoptosis and affects a distinct spectrum of tumor necrosis factor [corrected] target genes. J Biol Chem. 2005 Jul 29;280(30):27728–41. doi: 10.1074/jbc.m411657200. PMID: 15837794.; Martín-Blanco E. p38 MAPK signalling cascades: ancient roles and new functions. Bioessays. 2000 Jul;22(7):637–45. doi: 10.1002/1521-1878(200007)22:7<637::aid-bies6>3.0.co;2-e. PMID: 10878576.; Raingeaud J, Whitmarsh AJ, Barrett T, Dérijard B, Davis RJ. MKK3- and MKK6-Regulated Gene Expression Is Mediated by the p38 Mitogen-Activated Protein Kinase Signal Transduction Pathway. Molecular and Cellular Biology. 1996 Mar 01;16(3):1247–55. doi: 10.1128/mcb.16.3.1247.; Yamaguchi K, Shirakabe K, Shibuya H, Irie K, Oishi I, Ueno N, Taniguchi T, Nishida E, Matsumoto K. Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction. Science. 1995 Dec 22;270(5244):2008–11. doi: 10.1126/science.270.5244.2008. PMID: 8533096.