MTOR signalling

Laplante M, Sabatini DM. mTOR signaling in growth control and disease. Cell. 2012 Apr 13;149(2):274–93. PMID: 22500797; PMCID: PMC3331679.; Zoncu R, Efeyan A, Sabatini DM. mTOR: from growth signal integration to cancer, diabetes and ageing. Nature Reviews Molecular Cell Biology. 2010 Dec 15;12(1):21–35. doi: 10.1038/nrm3025.

Metabolites

adenosine 5'-monophosphate(2-)

Formula: C10H12N5O7P (345.0474332)

CAS ID:

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:

GTP(4-)

Formula: C10H12N5O14P3 (518.9593642)

CAS ID: 86527-72-2

ADP(3-)

Formula: C10H12N5O10P2 (424.0059412)

CAS ID:



Enzyme

EC Number name full name note
3.6.5.-
2.7.11.1 non-specific serine/threonine protein kinase ATP:protein phosphotransferase (non-specific)
5.2.1.8 peptidylprolyl isomerase Peptidylproline cis-trans-isomerase


Proteins

Protein ID name full name
O42993 fkh1 Peptidyl-prolyl cis-trans isomerase
O74544 gtr2 GTP-binding protein gtr2
O74824 gtr1 GTP-binding protein gtr1
O94363 rhb1 GTP-binding protein rhb1
P50530 sck1 Serine/threonine-protein kinase sck1
Q12706 psk1 Serine/threonine-protein kinase psk1