Signaling by PDGF
Fredriksson L, Li H, Eriksson U. The PDGF family: four gene products form five dimeric isoforms. Cytokine Growth Factor Rev. 2004 Aug;15(4):197–204. doi: 10.1016/j.cytogfr.2004.03.007. PMID: 15207811.; Heldin CH, Westermark B. Mechanism of action and in vivo role of platelet-derived growth factor. Physiol Rev. 1999 Oct;79(4):1283–316. doi: 10.1152/physrev.1999.79.4.1283. PMID: 10508235.; Heldin C, Östman A, Rönnstrand L. Signal transduction via platelet-derived growth factor receptors. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer. 1998 Aug;1378(1):F79–F113. doi: 10.1016/s0304-419x(98)00015-8.
Metabolites
Enzyme
| EC Number | name | full name | note |
|---|---|---|---|
| 2.7.10.1 | receptor protein-tyrosine kinase | ATP:[protein]-L-tyrosine O-phosphotransferase (receptor-type) | |
| 2.7.10.2 | non-specific protein-tyrosine kinase | ATP:[protein]-L-tyrosine O-phosphotransferase (non-specific) | |
| 3.1.3.48 | protein-tyrosine-phosphatase | protein-tyrosine-phosphate phosphohydrolase | |
| 3.1.4.11 | phosphoinositide phospholipase C | 1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase | |
| 3.4.21.75 | Furin |
Proteins
| Protein ID | name | full name |
|---|