NTF3 activates NTRK3 signaling
Werner P, Paluru P, Simpson AM, Latney B, Iyer R, Brodeur GM, Goldmuntz E. Mutations inNTRK3Suggest a Novel Signaling Pathway in Human Congenital Heart Disease. Human Mutation. 2014 Nov 07;35(12):1459–68. doi: 10.1002/humu.22688.; Huang EJ, Reichardt LF. Neurotrophins: Roles in Neuronal Development and Function. Annu. Rev. Neurosci. 2001 Mar;24(1):677–736. doi: 10.1146/annurev.neuro.24.1.677.; Tsoulfas P, Stephens RM, Kaplan DR, Parada LF. TrkC Isoforms with Inserts in the Kinase Domain Show Impaired Signaling Responses. Journal of Biological Chemistry. 1996 Mar;271(10):5691–7. doi: 10.1074/jbc.271.10.5691.; Philo J, Talvenheimo J, Wen J, Rosenfeld R, Welcher A, Arakawa T. Interactions of neurotrophin-3 (NT-3), brain-derived neurotrophic factor (BDNF), and the NT-3.BDNF heterodimer with the extracellular domains of the TrkB and TrkC receptors. Journal of Biological Chemistry. 1994 Nov;269(45):27840–6. doi: 10.1016/s0021-9258(18)46863-9.; Lamballe F, Klein R, Barbacid M. trkC, a new member of the trk family of tyrosine protein kinases, is a receptor for neurotrophin-3. Cell. 1991 Sep 06;66(5):967–79. doi: 10.1016/0092-8674(91)90442-2. PMID: 1653651.