Metabolism of RNA

Hocine S, Singer RH, Grunwald D. RNA Processing and Export. Cold Spring Harbor Perspectives in Biology. 2010 Oct 20;2(12):a000752. doi: 10.1101/cshperspect.a000752.

Metabolites

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Magnesium cation

Formula: Mg (23.98505)

CAS ID: 22537-22-0

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:

GTP(4-)

Formula: C10H12N5O14P3 (518.9593642)

CAS ID: 86527-72-2

ADP(3-)

Formula: C10H12N5O10P2 (424.0059412)

CAS ID:



Enzyme

EC Number name full name note
2.1.1.-
2.1.1.56 mRNA (guanine-N7)-methyltransferase S-adenosyl-L-methionine:mRNA (guanine-N7)-methyltransferase
2.3.2.27 RING-type E3 ubiquitin transferase [E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine:[acceptor protein] ubiquitin transferase (isopeptide bond-forming; RING-type)
2.7.11.1 non-specific serine/threonine protein kinase ATP:protein phosphotransferase (non-specific)
2.7.11.23 [RNA-polymerase]-subunit kinase ATP:[DNA-directed RNA polymerase] phosphotransferase
2.7.7.19 polynucleotide adenylyltransferase ATP:polynucleotide adenylyltransferase
2.7.7.50 mRNA guanylyltransferase GTP:mRNA guanylyltransferase
3.1.13.4 poly(A)-specific ribonuclease
3.1.26.5 ribonuclease P
3.1.3.16 protein-serine/threonine phosphatase protein-serine/threonine-phosphate phosphohydrolase
3.6.1.59 5'-(N7-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase 5'-(N7-methyl 5'-triphosphoguanosine)-[mRNA] N7-methylguanosine 5'-phosphate phosphohydrolase
3.6.4.12 DNA helicase
3.6.4.13 RNA helicase
5.2.1.8 peptidylprolyl isomerase Peptidylproline cis-trans-isomerase
5.6.2.3 DNA 5'-3' helicase DNA 5'-3' helicase (ATP-hydrolysing)
5.6.2.4 DNA 3'-5' helicase DNA 3'-5' helicase (ATP-hydrolysing)


Proteins

Protein ID name full name
O13768 ptr8 General transcription and DNA repair factor IIH helicase/translocase subunit XPB
O13792 uap56 ATP-dependent RNA helicase uap56
O13794 ysh1 Endoribonuclease ysh1
O14011 prp19 Pre-mRNA-processing factor 19
O14232 mtr4 ATP-dependent RNA helicase mtr4
O42650 rio1 Serine/threonine-protein kinase rio1
O42945 prp43 Probable pre-mRNA-splicing factor ATP-dependent RNA helicase prp43
O42957 ulp1 Ubiquitin-like-specific protease 1
O59801 SKI2_SCHPO Putative ATP-dependent RNA helicase C550.03c
O74718 sup35 Eukaryotic peptide chain release factor GTP-binding subunit
O74774 hbs1 Elongation factor 1 alpha-like protein
O74880 pcm1 mRNA cap guanine-N(7) methyltransferase
O74942 cyp9 Peptidyl-prolyl cis-trans isomerase 9
P23636 ppa2 Major serine/threonine-protein phosphatase PP2A-2 catalytic subunit
P24782 dbp2 ATP-dependent RNA helicase dbp2
P26659 rad15 General transcription and DNA repair factor IIH helicase subunit XPD
P37202 dis3 Exosome complex exonuclease dis3
P40235 hhp1 Casein kinase I homolog hhp1
P40997 ceg1 mRNA-capping enzyme subunit alpha
P87051 ppi1 Peptidyl-prolyl cis-trans isomerase ppi1
P87120 RNP3_SCHPO Probable ribonuclease P protein subunit 3
Q09775 rok1 ATP-dependent RNA helicase rok1
Q09798 pan2 PAN2-PAN3 deadenylation complex catalytic subunit pan2
Q09820 upf1 ATP-dependent helicase upf1
Q09928 cyp8 Peptidyl-prolyl cis-trans isomerase cyp8
Q10055 tif412 ATP-dependent RNA helicase fal1
Q10107 mra1 Ribosomal RNA small subunit methyltransferase mra1
Q10146 rrp6 Exosome complex exonuclease rrp6
Q10162 bud23 18S rRNA (guanine-N(7))-methyltransferase bud23
Q10295 pla1 Poly(A) polymerase pla1
Q11004 wis2 40 kDa peptidyl-prolyl cis-trans isomerase
Q12126 crk1 Serine/threonine-protein kinase crk1
Q9HDY4 YK16_SCHPO Putative ATP-dependent RNA helicase PB1A10.06c
Q9HDZ9 QNG1_SCHPO Queuosine 5'-phosphate N-glycosylase/hydrolase
Q9HGM5 dbp8 ATP-dependent RNA helicase dbp8
Q9P6N8 rrp3 ATP-dependent rRNA helicase rrp3
Q9P774 prp16 Pre-mRNA-splicing factor ATP-dependent RNA helicase prp16
Q9P7C7 prp11 Pre-mRNA-processing ATP-dependent RNA helicase prp11
Q9P7C9 nhm1 m7GpppX diphosphatase
Q9P7W5 rio2 Serine/threonine-protein kinase rio2
Q9UT24 brr2 Pre-mRNA-splicing factor brr2
Q9UTK0 nob1 20S-pre-rRNA D-site endonuclease nob1
Q9UTK4 nup189 Nucleoporin nup189
Q9UU96 grc3 Polynucleotide 5'-hydroxyl-kinase grc3
Q9UUE4 cyp6 Peptidyl-prolyl cis-trans isomerase cyp6
Q9Y813 rpr2 Ribonuclease P protein subunit rpr2