Metabolism of RNA

Hocine S, Singer RH, Grunwald D. RNA Processing and Export. Cold Spring Harbor Perspectives in Biology. 2010 Oct 20;2(12):a000752. doi: 10.1101/cshperspect.a000752.

Metabolites

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

N7-Methylguanosine

Formula: C11H16N5O5 (298.1151386)

CAS ID: 20244-86-4

adenosine 5'-monophosphate(2-)

Formula: C10H12N5O7P (345.0474332)

CAS ID:

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:

GTP(4-)

Formula: C10H12N5O14P3 (518.9593642)

CAS ID: 86527-72-2

ADP(3-)

Formula: C10H12N5O10P2 (424.0059412)

CAS ID:



Enzyme

EC Number name full name note
2.7.1.-
2.1.1.260 rRNA small subunit pseudouridine methyltransferase Nep1 S-adenosyl-L-methionine:18S rRNA (pseudouridine1191-N1)-methyltransferase
2.1.1.309 18S rRNA (guanine1575-N7)-methyltransferase S-adenosyl-L-methionine:18S rRNA (guanine1575-N7)-methyltransferase
2.1.1.56 mRNA (guanine-N7)-methyltransferase S-adenosyl-L-methionine:mRNA (guanine-N7)-methyltransferase
2.7.11.1 non-specific serine/threonine protein kinase ATP:protein phosphotransferase (non-specific)
2.7.11.23 [RNA-polymerase]-subunit kinase ATP:[DNA-directed RNA polymerase] phosphotransferase
2.7.7.50 mRNA guanylyltransferase GTP:mRNA guanylyltransferase
3.1.13.4 poly(A)-specific ribonuclease
3.1.26.5 ribonuclease P
3.1.3.16 protein-serine/threonine phosphatase protein-serine/threonine-phosphate phosphohydrolase
3.6.1.59 5'-(N7-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase 5'-(N7-methyl 5'-triphosphoguanosine)-[mRNA] N7-methylguanosine 5'-phosphate phosphohydrolase
3.6.1.62 5'-(N7-methylguanosine 5'-triphospho)-[mRNA] hydrolase 5'-(N7-methylguanosine 5'-triphospho)-[mRNA] N7-methylguanosine-5'-diphosphate phosphohydrolase
3.6.4.12 DNA helicase
3.6.4.13 RNA helicase
5.6.2.3 DNA 5'-3' helicase DNA 5'-3' helicase (ATP-hydrolysing)
5.6.2.4 DNA 3'-5' helicase DNA 3'-5' helicase (ATP-hydrolysing)


Proteins

Protein ID name full name
P05453 SUP35 Eukaryotic peptide chain release factor GTP-binding subunit
P06242 KIN28 Serine/threonine-protein kinase KIN28
P06839 RAD3 General transcription and DNA repair factor IIH helicase subunit XPD/RAD3
P22147 XRN1 5'-3' exoribonuclease 1
P23594 PPH21 Serine/threonine-protein phosphatase PP2A-1 catalytic subunit
P25627 BUD23 18S rRNA (guanine(1575)-N(7))-methyltransferase
P29295 HRR25 Casein kinase I homolog HRR25
P30771 NAM7 ATP-dependent helicase NAM7
P32769 HBS1 Elongation factor 1 alpha-like protein
P32783 ABD1 mRNA cap guanine-N(7) methyltransferase
P35207 SKI2 Antiviral helicase SKI2
P38712 RRP3 ATP-dependent rRNA helicase RRP3
P38719 DBP8 ATP-dependent RNA helicase DBP8
P38786 RPP1 Ribonuclease P/MRP protein subunit RPP1
P39517 DHH1 ATP-dependent RNA helicase DHH1
P40160 RIO2 Serine/threonine-protein kinase RIO2
P40571 RPR2 Ribonuclease P protein subunit RPR2
P45818 ROK1 ATP-dependent RNA helicase ROK1
P47047 MTR4 ATP-dependent RNA helicase DOB1
P53010 PAN2 PAN2-PAN3 deadenylation complex catalytic subunit PAN2
P53550 DCP2 m7GpppN-mRNA hydrolase
Q00578 SSL2 General transcription and DNA repair factor IIH helicase/translocase subunit XPB/SSL2
Q01159 CEG1 mRNA-capping enzyme subunit alpha
Q04217 ECM16 Probable ATP-dependent RNA helicase DHR1
Q06151 DCS1 m7GpppX diphosphatase
Q06224 YSH1 Endoribonuclease YSH1
Q06287 EMG1 Ribosomal RNA small subunit methyltransferase NEP1
Q07845 GRC3 Polynucleotide 5'-hydroxyl-kinase GRC3
Q08162 DIS3 Exosome complex exonuclease DIS3
Q08444 NOB1 20S-pre-rRNA D-site endonuclease NOB1
Q12149 RRP6 Exosome complex exonuclease RRP6
Q12196 RIO1 Serine/threonine-protein kinase RIO1