Interleukin-17 signaling

Gu C, Wu L, Li X. IL-17 family: cytokines, receptors and signaling. Cytokine. 2013 Nov;64(2):477–85. PMID: 24011563; PMCID: PMC3867811.; Song X, Qian Y. The activation and regulation of IL-17 receptor mediated signaling. Cytokine. 2013 May;62(2):175–82. doi: 10.1016/j.cyto.2013.03.014. PMID: 23557798.; Kawaguchi M, Adachi M, Oda N, Kokubu F, Huang SK. IL-17 cytokine family. J Allergy Clin Immunol. 2004 Dec;114(6):1265–73; quiz 1274. doi: 10.1016/j.jaci.2004.10.019. PMID: 15577820.

Metabolites

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:

ADP(3-)

Formula: C10H12N5O10P2 (424.0059412)

CAS ID:



Enzyme

EC Number name full name note
2.3.2.27 RING-type E3 ubiquitin transferase [E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine:[acceptor protein] ubiquitin transferase (isopeptide bond-forming; RING-type)
2.7.11.1 non-specific serine/threonine protein kinase ATP:protein phosphotransferase (non-specific)
2.7.11.10 IkappaB kinase ATP:[IkappaB protein] phosphotransferase
2.7.11.24 mitogen-activated protein kinase ATP:protein phosphotransferase (MAPKK-activated)
2.7.11.25 mitogen-activated protein kinase kinase kinase ATP:protein phosphotransferase (MAPKKKK-activated)
2.7.12.2 mitogen-activated protein kinase kinase ATP:protein phosphotransferase (MAPKKK-activated)


Proteins

Protein ID name full name