DNA Damage Bypass
Saugar I, Ortiz-Bazán MÁ, Tercero JA. Tolerating DNA damage during eukaryotic chromosome replication. Exp Cell Res. 2014 Nov 15;329(1):170–7. doi: 10.1016/j.yexcr.2014.07.009. PMID: 25038291.; Ulrich HD. Timing and spacing of ubiquitin-dependent DNA damage bypass. FEBS Lett. 2011 Sep 16;585(18):2861–7. doi: 10.1016/j.febslet.2011.05.028. PMID: 21605556.; Takata K, Wood RD. Bypass specialists operate together. EMBO J. 2009 Feb 18;28(4):313–4. PMID: 19225445; PMCID: PMC2646159.; Zhu F, Zhang M. DNA polymerase zeta: new insight into eukaryotic mutagenesis and mammalian embryonic development. World J Gastroenterol. 2003 Jun;9(6):1165–9. PMID: 12800216; PMCID: PMC4611776.; Friedberg EC, Fischhaber PL, Kisker C. Error-prone DNA polymerases: novel structures and the benefits of infidelity. Cell. 2001 Oct 05;107(1):9–12. doi: 10.1016/s0092-8674(01)00509-8. PMID: 11595180.; Lehmann AR. Replication of UV-damaged DNA: new insights into links between DNA polymerases, mutagenesis and human disease. Gene. 2000 Jul 25;253(1):1–12. doi: 10.1016/s0378-1119(00)00250-x. PMID: 10925197.
Metabolites
Enzyme
| EC Number | name | full name | note |
|---|---|---|---|
| 3.1.11.- | |||
| 2.3.2.23 | E2 ubiquitin-conjugating enzyme | S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine:[E2 ubiquitin-conjugating enzyme] ubiquitinyl transferase | |
| 2.7.7.7 | DNA-directed DNA polymerase | deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) | |
| 3.4.19.12 | ubiquitinyl hydrolase 1 | ||
| 3.6.4.6 | vesicle-fusing ATPase | ATP phosphohydrolase (vesicle-fusing) |
Proteins
| Protein ID | name | full name |
|---|