InlB-mediated entry of Listeria monocytogenes into host cell

Dortet L, Veiga E, Bonazzi M, Cossart P. CD44-independent activation of the Met signaling pathway by HGF and InlB. Microbes Infect. 2010 Nov;12(12-13):919–27. doi: 10.1016/j.micinf.2010.07.009. PMID: 20670691.; Ferraris DM, Gherardi E, Di Y, Heinz DW, Niemann HH. Ligand-mediated dimerization of the Met receptor tyrosine kinase by the bacterial invasion protein InlB. J Mol Biol. 2010 Jan 22;395(3):522–32. doi: 10.1016/j.jmb.2009.10.074. PMID: 19900460.; Jung C, Matzke A, Niemann HH, Schwerk C, Tenenbaum T, Orian-Rousseau V. Involvement of CD44v6 in InlB-dependent Listeria invasion. Molecular Microbiology. 2009 May 22;72(5):1196–207. doi: 10.1111/j.1365-2958.2009.06716.x.; Niemann HH, Jäger V, Butler PJ, van den Heuvel J, Schmidt S, Ferraris D, Gherardi E, Heinz DW. Structure of the human receptor tyrosine kinase met in complex with the Listeria invasion protein InlB. Cell. 2007 Jul 27;130(2):235–46. doi: 10.1016/j.cell.2007.05.037. PMID: 17662939.; Veiga E, Cossart P. Listeria hijacks the clathrin-dependent endocytic machinery to invade mammalian cells. Nat Cell Biol. 2005 Sep;7(9):894–900. doi: 10.1038/ncb1292. PMID: 16113677.; Shen Y, Naujokas M, Park M, Ireton K. InIB-dependent internalization of Listeria is mediated by the Met receptor tyrosine kinase. Cell. 2000 Oct 27;103(3):501–10. doi: 10.1016/s0092-8674(00)00141-0. PMID: 11081636.

Metabolites

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:

ADP(3-)

Formula: C10H12N5O10P2 (424.0059412)

CAS ID:



Enzyme

EC Number name full name note
2.3.2.27 RING-type E3 ubiquitin transferase [E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine:[acceptor protein] ubiquitin transferase (isopeptide bond-forming; RING-type)
2.7.10.1 receptor protein-tyrosine kinase ATP:[protein]-L-tyrosine O-phosphotransferase (receptor-type)


Proteins

Protein ID name full name