Activated NTRK2 signals through PI3K

Cao C, Rioult-Pedotti MS, Migani P, Yu CJ, Tiwari R, Parang K, Spaller MR, Goebel DJ, Marshall J. Correction: Impairment of TrkB-PSD-95 Signaling in Angelman Syndrome. PLoS Biol. 2013 Mar 05;11(3). doi: 10.1371/annotation/f32bc670-c9cf-4bb0-9376-cd8cfd1053c1.; Yuen EC, Mobley WC. Early BDNF, NT-3, and NT-4 signaling events. Exp Neurol. 1999 Sep;159(1):297–308. doi: 10.1006/exnr.1999.7148. PMID: 10486198.

Metabolites

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:

ADP(3-)

Formula: C10H12N5O10P2 (424.0059412)

CAS ID:



Enzyme

EC Number name full name note
2.7.1.137 phosphatidylinositol 3-kinase ATP:1-phosphatidyl-1D-myo-inositol 3-phosphotransferase
2.7.1.153 phosphatidylinositol-4,5-bisphosphate 3-kinase ATP:1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate 3-phosphotransferase
2.7.10.1 receptor protein-tyrosine kinase ATP:[protein]-L-tyrosine O-phosphotransferase (receptor-type)
2.7.11.1 non-specific serine/threonine protein kinase ATP:protein phosphotransferase (non-specific)


Proteins

Protein ID name full name