Tie2 Signaling

Ward NL, Dumont DJ. The angiopoietins and Tie2/Tek: adding to the complexity of cardiovascular development. Seminars in Cell & Developmental Biology. 2002 Feb;13(1):19–27. doi: 10.1006/scdb.2001.0288.; Loughna S, Sato TN. Angiopoietin and Tie signaling pathways in vascular development. Matrix Biol. 2001 Sep;20(5-6):319–25. doi: 10.1016/s0945-053x(01)00149-4. PMID: 11566266.; Jones N, Dumont DJ. Tek/Tie2 signaling: new and old partners. Cancer Metastasis Rev. 2000;19(1-2):13–7. doi: 10.1023/a:1026555121511. PMID: 11191051.; Jones N, Dumont DJ. The Tek/Tie2 receptor signals through a novel Dok-related docking protein, Dok-R. Oncogene. 1998 Sep 03;17(9):1097–108. doi: 10.1038/sj.onc.1202115. PMID: 9764820.

Metabolites

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:

GTP(4-)

Formula: C10H12N5O14P3 (518.9593642)

CAS ID: 86527-72-2

ADP(3-)

Formula: C10H12N5O10P2 (424.0059412)

CAS ID:



Enzyme

EC Number name full name note
2.7.10.1 receptor protein-tyrosine kinase ATP:[protein]-L-tyrosine O-phosphotransferase (receptor-type)
3.1.3.48 protein-tyrosine-phosphatase protein-tyrosine-phosphate phosphohydrolase


Proteins

Protein ID name full name